Evaluation of the Ectopic Pregnancies Developed after in vitro Fertilisation in the Center of Assisted Reproduction CAR 01 Brno between 1988 – 2006

Overview

Objective:
To review prevalence and management of ectopic and heterotopic pregnancies developed after in vitro fertilisation and embryotranfer in the Center of Assisted Reproduction CAR 01 LF MU a FN Brno in a 20 – year period. An analysis of their management and therapy.

Design:
A retrospective analysis.

Setting:
Obstetrics and Gyneacology Department, University Hospital Brno.

Methods:
The collection of 1487 pregnancies arisen after IVF/ET cycles accomplished in the period of 1988 – 2006 in the Center of Assisted Reproduction CAR 01 Brno, in which the prevalence and the therapy of extrauterine and heterotopic pregnancies was observed. Also the therapeutic procedures of ectopic pregnancies and developement of heterotopic pregnancies were analysed.

Results:
In the follow-up file the numbers of ectopic pregnancies was 84 from 1487 (5.65%) clinical pregnancies. Heterotopic pregnancy occured in seven cases (0.47%). Both ectopic and heterotopic pregnancy rate is higher than in a common population. From the seven heterotopic pregnancies two resulted in the delivery of the intrauterine pregnancy. From the total number of 84 ectopic pregnancies 68 (88.10%) resulted in laparoscpic salpingectomy as the therapy, only nine of them (11.90%) were treated conservatively with the tube preservation.

Conclusion:
Evaluation of the ectopic and heterotopic rate prevalence after assisted conception treatment in the Centre of Assisted Reproduction CAR 01 Brno in the period of 1988 - 2006 shows higher appearance of these complications in pregnancies, which origin is in IVF and ET as an infertility treatment.

Key words:
ectopic pregnancy; heterotopic pregnancy; in vitro fertilisation; embryotransfer; kryoembryotransfer