A Role of Prenatal Diagnostics in Birth Defects Occurrence in the Czech Republic in 2004

Czech version

Authors: V. Gregor ^1,2; A. Šípek ^3,4; J. Horáček ^1,2; D. Mašátová ⁵
Authors‘ workplace: Oddělení lékařské genetiky, Fakultní Thomayerova nemocnice, Praha, ředitel MUDr. P. Malý ¹; Institut postgraduálního vzdělávání ve zdravotnictví, Praha, Katedra lékařské genetiky, ředitel MUDr. A. Malina, Ph. D., MBA ²; Ústav pro péči o matku a dítě, Praha-Podolí, ředitel doc. MUDr. J. Feyereisl, CSc. ³; Institut postgraduálního vzdělávání ve zdravotnictví, Praha, Katedra gyn. -por., ředitel MUDr. A. Malina Ph. D., MBA ⁴; Ústav zdravotnických informací a statistiky České republiky, Praha, ředitelka Mgr. V. Mazánková ⁵
Published in: Ceska Gynekol 2006; 71(5): 373-380
Category: Original Article

Overview

Objective:
An analysis of prenatal diagnostics of birth defects in the Czech Republic in 2004 and a comparison to data from 1996 – 2003.

Type of study:
A retrospective analysis of data from a Register of Prenatal Diagnostics of the Czech Republic.

Methodology:
Data on birth defects in the Czech Republic from particular departments of medical genetics and prenatal diagnostics from 1996 to 2004 time period was used. An analysis of data on prenatal diagnostics of selected type of birth defects was performed.

Results:
During 1996 to 2004 period, a total of 4,126 prenatally diagnosed and terminated cases were reported. In 2004, 597 cases were reported, which presents 61.1 cases per 10 000 live births. (The mean rate from the total period under the study was 49.8 per 10 000 live births.)

Conclusions:
Current data on birth defects in a 9-year period in the Czech Republic are presented. The role of prenatal diagnostics in decrease of some severe types of birth defects is underlined.

Key words:
birth defect, prenatal diagnostics, incidence, Czech Republic