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Dopaminergic Mechanisms in Depression and Antidepressant Drug Effects


Authors: A. Šulcová
Authors‘ workplace: Farmakologický ústav LF MU, Brno vedoucí prof. MUDr. A . Šulcová, CSc.
Published in: Čes. a slov. Psychiat., 104, 2008, No. 1, pp. 18-21.
Category: Comprehensive Reports

Overview

Both experimental and clinical studies are continuously bringing data suggesting a decreased activity of not only serotonergic and adrenergic but also of dopaminergic brain functioning. This corresponds well with successful therapy of depression with drugs acting either as agonists at postsynaptic dopamine receptors or inhibitors of dopamine reuptake.

Key words:
neurotransmitter dopamine, depression, mechanisms of antidepressants.


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Addictology Paediatric psychiatry Psychiatry
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