Causes and interventions of medication errors in healthcare facilities
Authors:
Jan Neugebauer; Valérie Tóthová; Ivana Chloubová; Hana Hajduchová; Iva Brabcová; Radka Prokešová
Authors‘ workplace:
Zdravotně sociální fakulta, Jihočeská univerzita v Českých Budějovicích
Published in:
Čes. slov. Farm., 2021; 70, 43-50
Category:
Original Article
doi:
https://doi.org/10.5817/CSF2021-2-43
Overview
A medication error is one of the most common causes of patients’ complications or death in healthcare facilities. In the United States, 7,000 out of 9,000 patients die because of medication errors each year. Known factors are generally divided into four groups – human factor, intervention, technical factor, and system.
Our study includes 17 studies from the OVID, Web of Science, Scopus, and EBSCO databases, in the range of 2015–2020. After a selection of professional publications, 2 categories were created – factors leading to medication errors and interventions to reduce medication error and testing their effectiveness.
It has been found that human factor always plays a role, often supported by a poorly set-up system. The most mistakes are made in documentation, administration technique or accidental interchange of patients. The most frequently mentioned factors include nurses’ overload, high number of critically ill patients, interruptions in the preparation or in the administration of medications, absence of the adverse event reporting system, non-compliance with guidelines, fear, and anxiety.
Another evidence of medication error is in the application of intravenous drugs, where an interchange of drugs or patients due to interruption occurs as well. Sufficient education of nurses and an adequate system of preparation and administration of drugs, for example using bar codes, are considered as an appropriate intervention.
Keywords:
medication error – drug preparation – Drug administration – factors of medication error – intervention
Sources
- Feleke S. A., Mulatu M. A., Yesmaw W Y. S. Medication administration error: magnitude and associated factors among nurses in Ethiopia. BMC Nursing 2015; 14(1).
- Brabcová I., Bártlová S., Tóthová V., Svobodová D. Medication errors from the perspective of health care management. Onkologie 2014; 8(4), 178–181.
- Wondmieneh A., Alemu W., Tadele N., Demis A. Medication administration errors and contributing factors among nurses: a cross sectional study in tertiary hospitals, Addis Ababa, Ethiopia. BMC Nursing 2020; 19(1).
- Butcher H. K., Bulechek G. M., Dochterman J. M., Wagner CH. M. Nursing Interventions Classification (NIC). 7th edition. Mosby 2019.
- Kaushal R. Medication Errors and Adverse Drug Events in Pediatric Inpatients. JAMA 2001; 285(16).
- Gallagher R. M., Mason J. R., Bird K. A., Kirkham J. J., Peak M., Williamson P. R., Nun A. J., Turner M. A., Pirmohamed M., Smyth R. L. Adverse drug reactions causing admission to a paediatric hospital. PLoS One 2012; 7(12), 50127. doi: 10.1371/journal.pone.0050127
- Parihar M, Passi G. R. Medical errors in pediatric practice. Indian Pediatr. 2008; 45(7), 586.
- Otero P, Leyton A, Mariani G, Cernadas J. M. C. Medication errors in pediatric inpatients: prevalence and results of a prevention program. Pediatrics. 2008; 122(3), 737–743. doi: 10.1542/peds.2008-0014
- Tariq R. A., Vashisht R., Sinha A., Scherbak Y. Medication errors. Treasure Island (FL): StatPearls Publishing 2020.
- Spruce L. Back to Basics: Medication Safety. AORN Journal 2020; 111(1), 103–112.
- Tóthová V., Bártlová S., Brabcová I., Hajduchová H., Doseděl M., Malý J., Vlček J. Knowledge of nurses in relation to the treatment of medicinal products. Kontakt 2020; 22(4), 214–221.
- Vyhláška č. 391/2017 Sb., ze dne 16. listopadu 2017 – vyhláška, kterou se mění vyhláška č. 55/2011 Sb., o činnostech zdravotnických pracovníků a jiných odborných pracovníků. In: Sbírka zákonů České republiky 2010. Nakladatelství MV ČR.
- Alqenae F. A., Steinke D., Keers R. N. Prevalence and Nature of Medication Errors and Medication-Related Harm Following Discharge from Hospital to Community Settings: A Systematic Review. Drug Safety 2020; 43(6), 517–537.
- Keers R. N., Williams S. D., Cooke J., Aahcroft D. M. Causes of Medication Administration Errors in Hospitals: a Systematic Review of Quantitative and Qualitative Evidence. Drug Safety 2013; 36(11), 1045–1067.
- Márquez-Hernández V. V., Fuentes-Colmenero A. L., Cañadas-Núñez F., di Muzio M., Giannetta N., Gutiérrez-Puertas L., Vaismoradi M. Factors related to medication errors in the preparation and administration of intravenous medication in the hospital environment. PLoS One 2019; 14(7).
- Härkänen M., Ahonen J., Kervinen M., Turunen H., Vehviläinen-Julkunen K. The factors associated with medication errors in adult medical and surgical inpatients: a direct observation approach with medication record reviews. Scandinavian Journal of Caring Sciences 2015; 29(2), 297–306.
- Fathi A., Hajizadeh M., Moradi K., Zandian H., Dezhkameh M., Kazemzadeh S., Rezaei S. Medication errors among nurses in teaching hospitals in the west of Iran: what we need to know about prevalence, types, and barriers to reporting Epidemiology and Health 2017; 39.
- Yung H. P., Yu S., Chu Ch., Hou I. Ch. Tang F. I. Nurses’ attitudes and perceived barriers to the reporting of medication administration errors. Journal of Nursing Management 2016; 24(5), 580–588.
- Soydemir D., Seren Intepeler S., Mert H. Barriers to Medical Error Reporting for Physicians and Nurses. Western Journal of Nursing Research 2017; 39(10), 1348–1363.
- Ayorinde M. O., Alabi B. I. Perception and contributing factors to medication administration errors among nurses in Nigeria. International Journal of Africa Nursing Sciences 2019; 11.
- Nkurunziza A., Chironda G., Mukeshimana M., Uwamahoro M. C., Umwangange M. L., Ngendahayo F. Factors contributing to medication administration errors and barriers to self-reporting among nurses: a review of literature. Rwanda Journal of Medicine and Health Sciences 2020; 2(3), 294–303.
- Gegan A. B. D., Elfattah E., Abu-Snieneh H. M. Nurses’ Perception of Factors Contributing to Medication Administration Errors. International Journal of Research in Pharmaceutical Sciences 2020; 11(1), 44–56.
- Berdot S., Roudot M., Schramm C., Katsahian S., Durieux P., Sabatier B. Interventions to reduce nurses’ medication administration errors in inpatient settings: A systematic review and meta-analysis. International Journal of Nursing Studies 2016; 53, 342–350.
- Lin J. CH., Lee T. T., Mills M. E. Evaluation of a Barcode Medication Administration Information System. CIN: Computers, Informatics. Nursing 2018; 36(12), 596–602.
- Manias E., Kusljic S., Wu A. Interventions to reduce medication errors in adult medical and surgical settings: a systematic review. Therapeutic Advances in Drug Safety 2020; 11.
- Musharyanti L., Claramita M., Haryanti F., Dwiprahasto I. Why do nursing students make medication errors? A qualitative study in Indonesia. Journal of Taibah University Medical Sciences 2019; 14(3), 282–288.
- Carlesi K. C., Padilha K. G., Toffoletto M. C., Henriquez-Roldán C., Juan M. A. C. Patient Safety Incidents and Nursing Workload. Revista Latino-Americana de Enfermagem 2017; 25.
- Pérez-Francisco D. H., Duarte-Clíments G., del Rosario-Melián J. M., Gómez-Salgado J., Romero-Martín M., Sánchez-Gómez M. B. Influence of Workload on Primary Care Nurses’ Health and Burnout, Patients’ Safety, and Quality of Care: Integrative Review. Healthcare 2020; 8(1).
- Gulpinar O. Gucal Guclu A. How to write a review article? Türk Üroloji Dergisi/Turkish Journal of Urology 2014; 39(1), 44–48.
- Heyn P. C., Meeks S., Pruchno R. Methodological Guidance for a Quality Review Article. The Gerontologist 2019; 59(2), 197–201.
- Ahn E. J., Kang H. Introduction to systematic review and meta-analysis. Korean Journal of Anesthesiology 2018; 71(2), 103–112.
- Baraki Z., Abay M., Tsegay L., Gerensea H., Kebede A., Teklay H. Medication administration error and contributing factors among pediatric inpatient in public hospitals of Tigray, northern Ethiopia. BMC Pediatrics 2018; 18(1).
- Al Tehewy M., Fahim H., Gad N. I., El Gafary M., Rahman S. A. Medication Administration Errors in a University Hospital. Journal of Patient Safety 2016; 12(1), 34–39.
- Bifftu B. B., Mekonnen B. Y. The Magnitude of Medication Administration Errors among Nurses in Ethiopia: a Systematic Review and Meta-analysis. Journal of Caring Sciences 2020; 9(1), 1–8.
- Raja B., Sajid A., Sherali S. Association of medication administration errors with interruption among nurses in public sector tertiary care hospitals. Pakistan Journal of Medical Sciences 2019; 35(5).
- Jin H., Chen H., Munechika M., Sano M., Kajihara Ch. The effect of workload on nurses’ non-observance errors in medication administration processes: A cross-sectional study. International Journal of Nursing Practice 2018; 24(5).
- Hammoudi B. M., Ismaile S., Abu Yahya O. Factors associated with medication administration errors and why nurses fail to report them. Scandinavian Journal of Caring Sciences 2018; 32(3), 1038–1046.
- Alemu W., Belachew T., Yimam I. Medication administration errors and contributing factors: A cross sectional study in two public hospitals in Southern Ethiopia. International Journal of Africa Nursing Sciences 2017; 7, 68–74.
- Lee E. Reporting of medication administration errors by nurses in South Korean hospitals. International Journal for Quality in Health Care 2017; 29(5), 728–734.
- Zarea K., Mohammadi A., Beiranvand S., Hassani F., Baraz S. Iranian nurses’ medication errors: A survey of the types, the causes, and the related factors. International Journal of Africa Nursing Sciences 2018; 8, 112–116.
- Gorgich E. A. Ch., Barfroshan S., Ghoreishi G., Yaghoobi M. Investigating the Causes of Medication Errors and Strategies to Prevention of Them from Nurses and Nursing Student Viewpoint. Global Journal of Health Science 2015; 8(8).
- Darawad M. W., Othaman E. H., Alosta M. R. Nurses’ satisfaction with barcode medication‐administration technology: Results of a cross‐sectional study. Nursing & Health Sciences 2019; 21(4), 461–469.
- Lim A. G., Honey M. L. L. New Graduate Nurses’ Knowledge and Skills in Medication Management: Implications for Clinical Settings. The Journal of Continuing Education in Nursing 2017; 48(6), 276–281.
- Holmqvist M., Ekstedt M., Walter S. R., Lehnbom E. C. Medication Management in Municipality-Based Healthcare. Home Healthcare Now 2018; 36(4), 238–246.
- Bell H. T., Granas A. G., Enmarker I., Omli R., Steinsbekk A. Nurses’ and pharmacists’ learning experiences from participating in interprofessional medication reviews for elderly in primary health care – a qualitative study. BMC Family Practice 2017; 18(1).
- Lin J. Ch., Lee T. T., Mills M. E. Evaluation of a Barcode Medication Administration Information System. CIN: Computers, Informatics, Nursing 2018; 36(12), 596–602.
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