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Evaluation of the Posterior Capsule Opacification in Different Types of Artificial Intraocular Lenses


Authors: J. Pozlerová;  J. Nekolová;  N. Jirásková;  P. Rozsíval
Authors‘ workplace: Oční klinika Lékařské fakulty Univerzity Karlovy a Fakultní nemocnice, Hradec Králové, přednosta prof. MUDr. Pavel Rozsíval, CSc.
Published in: Čes. a slov. Oftal., 65, 2009, No. 1, p. 12-15

Overview

Purpose:
To evaluate and compare posterior capsule opacification (PCO) incidence and the best-corrected visual acuity (BCVA) in patients who underwent the implantation of intraocular lens (IOL) made of polymethylmethacrylate (PMMA), or hydrophobic acrylic material, or silicone material. All patients were examined 7 years after the surgery at the Department of Ophthalmology, University Hospital, Hradec Králové, Czech Republic, E.U.

Methods:
In this 60 study, sixty eyes (44 patients) were evaluated; 20 eyes with IOLs made of PMMA with round edge, 20 eyes with IOLs made of hydrophobic acrylic material with square edge and 20 eyes with IOLs made of silicone material with round edge. They were examined 7 years after surgery. The eyes treated with Nd:YAG laser capsulotomy were excluded from the EPCO 2000 evaluation. The EPCO 2000 software (Evaluation of Posterior Capsule Opacification) was used for PCO assessment. The density of the opacification was graded clinically from 1 to 4. The BCVA, the PCO index for every PCO grade and total PCO index were compared.

Results:
Mean of total PCO index for PMMA IOLs was 0.451 ± 0.619; for hydrophobic acrylic IOLs 0.361 ±0.397; and for silicone IOLs 0.552 ± 0.372. During the examination, we have found the BCVA mean to be for PMMA IOLs 0.79 ± 0.26, for hydrophobic acrylic IOLs 0.87 ± 0.19, and silicone IOLs 0.78 ± 0.29 respectively. Twenty eyes of twenty patients required Nd:YAG laser capsulotomy: twelve eyes with PMMA IOLs, two eyes with hydrophobic acrylic IOLs, and six eyes with silicone IOLs.

Conclusions:
In this study, the difference in PCO incidence and BCVA among PMMA, hydrophobic acrylic, and silicone IOLs were not statistically significant. The highest incidence of the Nd:YAG laser capsulotomy was in the group of PMMA IOLs, then in silicone IOLs, and the lowest incidence was in the group of hydrophobic acrylic IOLs.

Key words:
posterior capsule opacification, PMMA IOL, hydrophobic acrylic IOL, silicone IOL, EPCO 2000


Sources

1. Adámková, H, Novák J.: Sekundární katarakta, její prevence a léčba. Část první: Prevence vzniku sekundární katarakty. Čes. a slov. Oftal., 62, 2006: 230–236.

2. Baráková, D., Kuchynka, P., Klečka, D. et al.: Frekvence výskytu sekundární katarakty u AcrySof MA30BA a MA60BM. Čes.a slov. Oftal., 56, 2000; 1: 38–42.

3. Buehl, W., Menapace, R., Sacu, S. et al: Effect of a silicone intraocular lens with a sharp posterior optic edge on posterior capsule opacification. J Cataract Refract Surg., 30, 2004: 1661–1667.

4. Buehl, W., Heinzl, H., Mittlboeck, M. et al: Statistical problems caused by missing data resulting from neodymium: YAG laser capsulotomies in long-term posterior capsule opacification studies. Problem identification and possible solutions. J Cataract Refract Surg., 34, 2008: 268–273.

5. Hayashi, K., Hayashi, H., Nakao, F. et al.: Capsular capture of silicone intraocular lenses. J Cataract Refract Surg., 22, 1996, Suppl. 2: 1267–1271.

6. Hayashi, H., Hayashi, K., Nakao, F. et al.: Quantitative comparison of posterior capsule opacification after polymethylmethacrylate, silicone, and soft acrylic intraocular lens implantation. Arch Ophthalmol., 116,1998: 1579–1582.

7. Hollick, EJ, Spalton, DJ, Ursell, PG et al.: The Effect of Polymethylmethacrylate, silicone, and polyacrylic intraocular lenses on posterior capsular opacification 3 years after cataract surgery. Ophthalmology, 106, 1999; 1: 46–55.

8. Jirásková, N., Rozsíval, P.: Metody hodnocení zkalení zadního pouzdra po operaci katarakty. Čes a slov. Oftal., 60, 2004; 2: 155–157.

9. Jirásková, N.: Pokroky v designu a materiálech nitroočních čoček. In Rozsíval, P. (Ed.) Trendy soudobé oftalmologie. Svazek 2. Praha: Galén, 2005, s. 263–283.

10. Jirásková, N., Kadlecová, J., Rozsíval, P. et al: Comparison of the effect of AquaLase and NeoSonix on the corneal endothelium. J Cataract Refract Surg 34, 2008; 3: 377–382.

11. Linnola, R.: The sandwich theory: a bioactivity based explanation for posterior capsule opacification after cataract surgery with lens implantation. Dissertation; University of Oulu. Acta Univ Oul., 2001; D 632: 89.

12. Nekolová, J., Pozlerová, J., Jirásková, N. et al: Comparison of posterior capsule opacification after two different surgical methods of cataract extraction. Am J Ophthalmol., 145, 2008; 3: 493–498.

13. Oner, FH, Gunenc, Ü., Ferliel, ST.: Posterior capsule opacification after phacoemulsification: Foldable acrylic versus poly(methyl methacrylate) intraocular lenses. J Cataract Refract Surg., 26, 2000: 722–726.

14. Sacu, S., Findl, O., Menapace, R. et al.: Influence of optic edge design, optic material, and haptic design on capsular bend configuration. J Cataract Refract Surg., 31, 2005:1888–1894.

15. Spalton, DJ: Posterior capsular opacification after cataract surgery. Eye, 13, 1999: 489–492.

16. Tetz , MR, Auffarth, GU, Speaker, M. et al.: Photographic image analysis system of posterior capsule opacification. J Cataract Refract Surg., 23, 1997: 1515–1519.

17. Tetz, M., Wildeck, A.: Evaluating and defining the sharpness of intraocular lenses; Part 1: Influence of optic design on growth of the lens epithelial cells in vitro. J Cataract Refract Surg., 31, 2005: 2172–2179.

18. Ursell, PG, Spalton, DJ, Pande, MV et al: Relationship between intraocular lens biomaterials and posterior capsule opacification. J Cataract Refract Surg, 24,1998: 352–360.

19. Werner, L., Miller, M., Tetz, M.: Evaluating and defining the sharpness of intraocular lenses; Microedge structure of commercially available square-edged hydrophobic lenses. J Cataract Refract Surg., 34, 2008: 310–317.

20. Žemaitiené, R., Jašinskas, V., Brzd, V. et al.: Prevention of posterior capsule opacification using different intraocular lenses (result of one-year clinical study). Medicina (Kaunas), 40, 2004; 8: 721–729.

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Czech and Slovak Ophthalmology

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