Radiological Findings in Term-neonates with Hypoxic-ischemic Encephalopathy

Czech version

Authors: L. Bakaj Zbrožková ¹; J. Hálek ^2,3; K. Michálková ¹; M. Heřman ¹
Authors‘ workplace: Radiologická klinika LF UP a FN Olomouc ¹; Novorozenecké oddělení, FN Olomouc ²; Dětská klinika LF UP a FN Olomouc ³
Published in: Cesk Slov Neurol N 2017; 80/113(3): 291-299
Category: Original Paper

Práce byla podpořena grantem UP: IGA_LF_2016_004 a RVO: LF UP 61989592.

Overview

Aim:
The analysis of ultrasonographic and MRI brain findings in term neonates with hypoxic-ischemic encephalopathy referred for therapeutic hypothermia.

Material and methods:
The study included 39 neonates (25 boys and 14 girls). In 32 cases (82%) US was done during the therapeutic hypothermia, in seven cases (18%) after it ‘s completition. The brain MRI was performed after the therapy in all cases. Subsequently the results from the imaging methods were analyzed.

Results:
The most common pathological US findings were low value of the resistive index (53.1% during the hypothermia, 42.9% after it’s completition), the basal ganglia and thalamus injury (15.6% during the hypothermia, 28.6% after it’s completition) and diffuse increased echogenicity of the brain parenchyma (12.8% during the hypothermia). The dominant findings on the brain MRI were the basal ganglia and thalami injuries (82.1%), followed by cortical and subcortical lesions (35.9%) and changes of the posterior limb of the internal capsula (30.8%). The haemorrhage occured in high percentage (35.9%).

Conclusion:
Pathological US brain findings in neonates with hypoxic-ischemic encephalopathy performed during the therapy and after the treatment were present in 68.7% and 57.1%, resp. MRI examinations depicted pathology in 82.1%.

Key words:
hypoxic-ischemic encephalopathy – magnetic resonance imaging – neonate – ultrasonography

The authors declare they have no potential conflicts of interest concerning drugs, products, or services used in the study.

The Editorial Board declares that the manuscript met the ICMJE “uniform requirements” for biomedical papers.

Chinese summary - 摘要

缺氧缺血性脑病新生患儿放射学检查结果

目标：

超声检查（US）和MRI脑组织发现缺氧缺血性脑病的新生儿分为治疗性低温。

材料和方法：

该研究包括39名新生儿（25名男孩和14名女孩）。 32例（82％）超声检查在治疗低温期间完成，7例（18％）完成后完成。在所有情况下，在治疗后进行脑部MRI扫描。随后，分析了脑影像结果。

结果：

最常见的病理学超声检查研究结果是阻力指数（低体温53.1％，完成后为42.9％），基底神经节和丘脑损伤（低体温15.6％，完成完成后为28.6％）;扩散增加脑实质的回声（12.8％在低体温）。脑MRI的主要发现是基底神经节和丘脑损伤（82.1％），其次是皮层和皮质下病变（35.9％），内囊囊后肢变化（30.8％）。出血发生率高达35.9％。

结论：

在治疗期间和治疗后进行的缺氧缺血性脑病的新生儿的超声检查大脑病理学发现分别为68.7％和57.1％。 MRI检查显示病变在82.1％。

关键词：

缺氧缺血性脑病 - 磁共振成像 - 新生儿超声检查

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