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Extreme Hypertrophy of Peripheral Neuronal Structures in CIDP – a Case Study


Authors: J. Michalik 1;  E. Kurča 1;  M. Hladká 2;  B. Hofericová 1;  V. Nosáľ 1;  M. Grofik 1;  E. Kantorová 1;  M. Adámková 1
Authors‘ workplace: JLF UK a UN Martin Neurologická klinika 1;  JLF UK a UN Martin Rádiologická klinika 2
Published in: Cesk Slov Neurol N 2011; 74/107(1): 72-75
Category: Case Report

Overview

Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an autoimmune peripheral nerve disease characterized by flaccid quadriparesis with loss of sensitivity and possible damage to cranial nerves. The diagnosis of CIDP nay involve electromyography (EMG), cerebrospinal fluid analysis, nerve biopsy, magnetic resonance imaging (MRI) of peripheral nerves and the clinical response to immunosuppression and/or immunomodulation. MRI facilitates early detection of nerve hypertrophy. In our case report we present an unusual CIDP with extreme hypertrophy of the peripheral nerves and spinal roots.

Key words:
chronic inflammatory demyelinating polyradiculoneuropathy – hypertrophy – magnetic resonance imaging


Sources

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2. Matsuoka N, Kohriyama T, Ochi K, Nishitani M, Sueda Y, Mimori Y et al. Detection of cervical nerve root hypertrophy by ultrasonography in chronic inflammatory demyelinating polyradiculoneuropathy. J Neurol Sci 2004; 219(1–2): 15–21.

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4. Freitas MR, Nascimento OJ, Soares CN, Brito AR, Domingues RC. Chronic inflammatory demyelinating polyradiculoneuropathy: two cases with cervical spinal cord compression. Arq Neuropsiquiatr 2005; 63(3): 666–669.

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6. Tazawa K, Matsuda M, Yoshida T, Shimojima Y, GonoT, Morita H et al. Spinal nerve root hypertrophy on MRI: clinical significance in the diagnosis of chronic inflammatory demyelinating polyradiculoneuropathy. Intern Med 2008; 47(23): 2019–2024.

7. Van den Bergh PY, Hadden RD, Bouche P, Cornblath DR,Hahn A, Illa I et al. European Federation of Neurological Societies/Peripheral Nerve Society Guideline on management of chronic inflammatory demyelinating polyradiculoneuropathy: report of a joint task force of the European Federation of Neurological Societies and the Peripheral Nerve Society – first revision. Eur J Neurol 2010; 17(3): 356–363.

Labels
Paediatric neurology Neurosurgery Neurology

Article was published in

Czech and Slovak Neurology and Neurosurgery


2011 Issue 1

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