Brain Actinomycosis – Case Reports

Czech version

Authors: L. Petroušová ¹; L. Rožnovský ¹; T. Hrbáč ²; J. Jančová ³
Authors‘ workplace: Klinika infekčního lékařství FN Ostrava, 2Neurochirurgická klinika FN Ostrava, 3Odbor mikrobiologie a parazitologie, Zdravotní ústav se sídlem v Ostravě ¹
Published in: Cesk Slov Neurol N 2009; 72/105(3): 270-273
Category: Case Report

Overview

Actinomycosis of the central nervo us system is rare. Only a few percents of pati ents hospitalized with actinomycosis develop CNS involvement. Two cases of actinomycotic brain abscess are presented. The di agnosis of the first pati ents with solitary abscess was established by histological examinati on. Culture of the multiple brain abscess of the second pati ent yi elded Actinomyces. The tre atment included ne urosurgery therapy and prolonged administrati on of benzylpenicillin. The first pati ent with one- ye ar antibi otic tre atment was cured with minimal sequelae. The second pati ent di ed after 4 months beca use of progressi on of actinomycosis and other seri o us complicati ons.

Key words:
actinomycosis – brain abscess – surgery – antibi otics

Sources

1. Russo TA. Agents of actinomycosis. In: Mandel GL, Bennett JE, Dolin R (eds). Principles and practice of infecti o us dise ases. 6th ed. Philadelphi a: Elsevi er Churchill Livingstone 2005: 2924– 2934.

2. Dailey AT, LeRo ux PD, Grady MS. Resoluti on of an actinomycotic abscess with nonsurgical tre atment: case report. Ne urosurgery 1993; 32(1): 134– 136.

3. Jamjo om AB. Jamjo om ZA, al- Hedaithy SS. Actinomycotic brain abscess successfully tre ated by burr hole aspirati on and short co urse antimicrobi al therapy. Br J Ne urosurg. 1994; 8(5): 545– 550.

4. Puzzilli F, Salvati M, Ruggeri A, Raco A, Bristot R, Basti anello S et al. Intracrani al actinomycosis in juvenile pati ents. Childs Nerv Syst 1998; 14(9): 463– 466.

5. Smego RA jr. Actinomycosis of central nervo us system. Rev Infect Dis 1987; 9(5): 855– 865.

6. Ewald C, Kuhn S, Kalff R. Pyogenic infecti ons of the central nervo us system secondary to dental affecti ons- a report of six cases. Ne urosurg Rev 2006; 29(2): 163– 166.

7. Sommer F, Aldini R, Kolodzi ejczyk D. Systemic antibi otic therapy on multiple intracerebral abscesses of unknown origin. Acta Ne urochirur (Wi en) 1998; 140(10): 1095– 1096.

8. Tattevin P, Bruneel F, Clair B, Lello uche F, de Bro ucker T, Chevret S et al. Bacteri al brain abscesses: a retrospective study of 94 pati ents admitted to an intensive care unit (1980 to 1999). Am J Med 2003(1): 143– 146.

9. Binková H, Urbánková P, Hložek J, Svoboda J. Cervikofaci ální aktinomykóza. Otorinolaryng a Foni at 2003; 52(3): 145– 148.

10. Kepák T, Zapletal O, Skotáková J, Fabi án P, Habanec T. Teyschl O et al. Aktinomykóza břišní stěny a retroperitone a mimikující nádor přední břišní stěny. Čes- slov Pedi at 2003; 58(3): 141– 143.

11. Poljak V, Krč I, Ehrman J. Aktinomykóza. In: Poljak V, Krč I, Ehrman J (eds). Manu ál infekčních nemocí. 1st ed. Březsko: Solen 2000: 39– 40.