Turbulence srdeční frekvence v posouzení kardiální autonomní funkce u migreniků

English version

Authors: A. Avsar ¹; M. Yaman ²; C. Kilit ¹; M. Melek ¹; H. Saglam ¹; E. Onrat ¹
Authors‘ workplace: Department of Cardiology, School of Medicine, Afyon Kocatepe University, Afyonkarahisar, Turkey ¹; Department of Neurology, School of Medicine, Afyon Kocatepe University, Afyonkarahisar, Turkey ²
Published in: Cesk Slov Neurol N 2007; 70/103(2): 174-177
Category: Original Paper

Overview

Studie autonomní funkce u pacientů s migrénou nám dávají protichůdné výsledky. Turbulence srdeční frekvence (HRT) je novou metodou používanou k hodnocení kardiální autonomní funkce. Zhoršená HRT odráží kardiální autonomní dysfunkci. Cílem této studie bylo určit validaci HRT jakožto testu autonomní funkce u migreniků a srovnat ji s normální populací. Studie zahrnovala 44 pacientů s migrénou a 50 zdravých jedinců. Zaznamenávali jsme ambulantní 24hodinové elektrokardiogramy a vypočítali jsme parametry HRT, nástup turbulence (TO) a strmost turbulence (TS). HRT nemohla být vypočtena u 16 migreniků a 24 kontrol, protože tyto výpočty nelze provádět u subjektů, u kterých v záznamech Holteru chybí komorové extrasystoly. Tito pacienti byli ze statistických analýz vyloučeni. HRT jsme vypočítali u 28 migreniků (průměrný věk 47,4 ± 10,1 roků, 20 žen) a 28 kontrol (průměrný věk 47,5 ± 11, 6 roků, 20 žen). Ve dvou parametrech HRT nebyly zjištěny žádné významné rozdíly; TO a TS mezi migreniky a kontrolami (TO migreniků: -0,65 ± 3,84%, TO kontrol: –0,61 ± 4,42%, p = 0,38; TS migreniků: 9,34 ± ± 7,50 ms/RR, TS kontrol: 8,82 ± 6,34 ms /RR, p = 0,40). Zdá se, že parametry HRT, které určují kardiální autonomní dysfunkci, se u pacientů s migrénou nezměnily.

Klíčová slova:
kardiální autonomní funkce – turbulence srdeční frekvence – migréna

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