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Precancerous Conditions and Lesions of the Stomach


Authors: Přemysl Falt 1,2;  M. Hanousek 1;  E. Kundratová 1;  O. Urban 1,2
Published in: Klin Onkol 2013; 26(Supplementum): 22-28

Overview

Gastric carcinoma is a common malignant disease associated with an unfavorable prognosis in the case of late dia­gnosis. The most significant precancerous condition is chronic atrophic gastritis and intestinal metaplasia caused by Helicobacter pylori infection. These long‑lasting changes may lead to formation of dysplastic precancerous lesions. Upper endoscopy and histologic examination of forceps bio­psy specimens play a key role in the dia­gnosis of gastric precancerous conditions and lesions. Helicobacter pylori eradication therapy and endoscopic surveillance are main therapeutic modalities of gastric precancerous conditions. Localized precancerous lesions and early gastric neoplasia without the risk of lymphatic spread could be cured by means of endoscopic resection techniques.

Key words:
gastric cancer –  precancerous conditions –  gastritis –  Helicobacter pylori –  gastroscopy

The authors declare they have no potential conflicts of interest concerning drugs, products, or services used in the study.

The Editorial Board declares that the manuscript met the ICMJE “uniform requirements” for biomedical papers.

Submitted:
16. 9. 2013

Accepted:
27. 9. 2013


Sources

1. Svod.cz [internetová stránka]. Epidemiologie zhoubných nádorů v České republice. Masarykova univerzita, Česká republika. Dostupné z: www.svod.cz.

2. Hisachimi S, Sugawara N, Fukao A. Effectiveness of gastric mass screening in Japan. Cancer Detect Prev 1988; 11(3– 6): 323– 328.

3. Borchard F. Classification of gastric carcinoma. Hepatogastroenterology 1990; 37(2): 223– 232.

4. Hrdlička L, Šťovíček J. Dia­gnostika a symptomy. In: Šimša J et al (eds). Karcinom žaludku: současná dia­gnostika a léčba. Praha: Maxdorf 2012.

5. Abrams JA, Wang TC. Adenocarcinoma and other tumors of the stomach. In: Feldman M, Friedman LS, Brandt LJ et al (eds). Sleisinger and Fordtrans’s Gastrointestinal and Liver Disease. 9th ed. Philadelphia: Elsevier Saunders 2010.

6. Hrdlička L, Šťovíček J. Etiologické faktory. In: Šimša J et al (eds). Karcinom žaludku: současná dia­gnostika a léčba. Praha: Maxdorf 2012.

7. Jirásek T. Histomorfologický obraz prekanceróz. In: Černoch J et al (eds). Prekancerózy v trávicím traktu. 1. vyd. Praha: Grada 2012: 45– 74.

8. Correa P. Human gastric carcinogenesis: a multistep and multifactorial process –  First American Cancer Society Award Lecture on Cancer Epidemiology and Prevention. Cancer Res 1992; 52(24): 6735– 6740.

9. Dinis‑ Ribeiro M, Areia M, de Vries AC et al. Management of precancerous conditions and lesions in the stomach (MAPS): guideline from the European Society of Gastrointestinal Endoscopy (ESGE), European Helicobacter Study Group (EHSG), European Society of Pathology (ESP) and the Sociedade Portuguesa de Endoscopia Digestiva. Endoscopy 2012; 44(1): 74– 94.

10. Bureš J, Kopáčová M, Rejchrt S. Pokles prevalence infekce Helicobacter pylori v České republice. Čas Lék Čes 2008; 147: 255– 257.

11. Lee EL, Feldman M. Gastritis and Gastropathies. In: Feldman M, Friedman LS, Brandt LJ et al (eds). Sleisinger and Fordtrans’s Gastrointestinal and Liver Disease. 9th ed. Philadelphia: Elsevier Saunders 2010.

12. Molloy RM, Sonnenberg A. Relation between gastric cancer and previous peptic ulcer disease. Gut 1997; 40(2): 247– 252.

13. Lauwers GY, Carneiro F, Graham DY et al. Gastric carcinoma. In: Bosman FT, Carneiro F, Hruban RH et al (eds). WHO Classification of Tumours of the Digestive Systém. 4th ed. Lyon: IARC Press 2010: 48– 58.

14. Urban O. Endoskopická léčba časného karcinomu žaludku. In: Šimša J et al (eds). Karcinom žaludku: současná dia­gnostika a léčba. Praha: Maxdorf 2012.

15. Urban O, Falt P. Endoskopická léčba prekanceróz a časných neoplázií trávicí trubice. In: Černoch J et al (eds). Prekancerózy v trávicím traktu. 1. vyd. Praha: Grada 2012: 151– 188.

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