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Precancerous Conditions in the ENT Area


Authors: B. Gál 1;  L. Mrzena 2;  P. Hort 3
Authors‘ workplace: Klinika otorinolaryngologie a chirurgie hlavy a krku LF MU a FN u sv. Anny v Brně 1;  Klinika otorinolaryngologie a chirurgie hlavy a krku 1. LF UK a FN v Motole 2;  ORL oddělení, Vojenská nemocnice Brno 3
Published in: Klin Onkol 2013; 26(Supplementum): 13-16

Overview

An important part of tumor prevention is early detection, dia­gnosis, treatment and screening of precancerous conditions. Correct detection and screening of premalignant lesions leads to early dia­gnosis of a malignant process which provides a better chance to completely cure the patient and also predicts better quality of life. Precancerous conditions look like whitish, red or mixed mucose lesions (leukoplakia, erytroplakia, erytroleukoplakia) which are visible during clinical examination. Nevertheless, these mucose changes are not absolutely conclusive. Therefore, histological testing is necessary for dia­gnosis and determination of bio­logical potencial of precancerous lesions. Precancerous lesions as a term of histological terminology means dysplasia. The risk of progression of dysplasia into a carcinoma depends on a grade of dysplasia. The conservative or surgical treatment is chosen according to localisation and grade of dysplasia.

Key words:
precancerous condition –  premalignant lesion –  ENT –  dysplasia –  leukoplakia –  erytroplakia – carcinoma in situ

The authors declare they have no potential conflicts of interest concerning drugs, products, or services used in the study.

The Editorial Board declares that the manuscript met the ICMJE “uniform requirements” for biomedical papers.

Submitted:
15. 9. 2013

Accepted:
17. 10. 2013


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Paediatric clinical oncology Surgery Clinical oncology
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