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Levosimendan in patients with mechanical circulatory support


Authors: MUDr. Hynek Říha, Ph.D.;  Fccp 1,2;  MUDr. Petr Syrovátka;  Ph.D. 1;  MUDr. Petr Kramář 1;  MUDr. Marian Pinďák 1;  MUDr. Leona Říhová 1;  MUDr. Zdeněk Matloch 1;  MUDr. Ivan Netuka;  Ph.D. 3;  MUDr. Tomáš Kotulák 1,2
Authors‘ workplace: Klinika anesteziologie a resuscitace Kardiocentrum IKEM, Praha 1;  Klinika anesteziologie, resuscitace a intenzivní medicíny, 1. LF UK, Praha 2;  Klinika kardiovaskulární chirurgie Kardiocentrum IKEM, Praha hynek. riha@ikem. cz 3
Published in: Kardiol Rev Int Med 2013, 15(2): 104-106
Category:

Overview

Levosimendan, calcium- sensitizer, is the last addition to inotropes available in clinical practice. It belongs to the group of inodilators, i.e., it increases myocardial contractility and concurrently decreases vascular resistance in pulmonary and systemic vascular beds. Levosimendan has favourable pharmacokinetics with active metabolite. All of these positive properties and effects are used in the patients before, during and after the implantation of different types of mechanical circulatory support devices.

Keywords:
levosimendan –  heart failure –  mechanical circulatory support


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Paediatric cardiology Internal medicine Cardiac surgery Cardiology
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