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The future of dyslipidemia therapy


Authors: V. Chaloupka
Authors‘ workplace: Interní kardiologická klinika FN Brno-Bohunice
Published in: Kardiol Rev Int Med 2009, 11(4): 191-196
Category: Notice

Overview

Currently, statins represent the key drug group for management of dyslipidemias. They importantly reduce concentration of cholesterol in low‑density lipoproteins. A number of patients do not achieve target values for the total as well as LDL‑cholesterol. Most frequently, this is because physicians prescribe too low doses of statins in monotherapy, and do not increase these doses, as well as because of the absence of combination therapy that represents the future of dyslipidemia treatment. The statin/ezetimibe or statin/fibrate combinations are common at present; the statin/fibrate/ezetimibe combination might also be used. The well‑tested niacin is soon to be available on the market (niacin/laropiprant), thus importantly broadening the combination therapy options.

Key words:
dyslipidemia – statins – fibrates – ezetimibe – niacin – combination therapy


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