Pulmonary Hypertension in Patients with Chronic Obstructive Pulmonary Disease
Authors:
Z. Merta
Authors‘ workplace:
Klinika nemocí plicních a TBC FN Brno
Published in:
Kardiol Rev Int Med 2009, 11(4): 178-180
Category:
Sympozium
Overview
Pulmonary hypertension (PH) is not a disease as such but rather a haemodynamic consequence of a variety of diseases, both pulmonary and cardiovascular. However, there is a small but important subgroup considered as idiopathic (idiopathic pulmonary arterial hypertension – IPAH). Otherwise – unlike in systemic hypertension – the origin of PH is mostly secondary. Pulmonary hypertension is a syndrome defined by the elevation of the mean pulmonary artery pressure (PAP) to > 25 mmHg at rest, or > 30 mmHg during exercise. Chronic obstructive pulmonary disease (COPD), the prevalence of which increased during the past decade, is a major cause of morbidity and mortality worldwide. One well‑known complication of COPD is PH – a condition that was previously known as ‘cor pulmonale’. Owing to its frequency, COPD is by far the most common cause of PH, far more common than other entities occurring within the latest WHO classification of PH (The Venice Classification, 2003). Although PH is frequently observed in patients with advanced COPD, the prevalence of PH is still unknown. At present, PH is considered a marker of the duration and severity of COPD. Mild to moderate degree of PH is probably the most important characteristic of COPD‑associated PH; this, in turn, provides some opportunities for treatment or improvement.
Keywords:
pulmonary hypertension – chronic obstructive pulmonary disease – pathogenesis and prognosis of PH in COPD
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Paediatric cardiology Internal medicine Cardiac surgery CardiologyArticle was published in
Cardiology Review
2009 Issue 4
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