Akutní krvácení u Crohnovy choroby

Acute Bleeding in the Crohn’s Disease

Acute bleeding is a rare, however a very serious complication of the Crohn‘s disease. Stabilization of the circulation, identification of its source and a consecutive therapeutical strategy remain the principal problem of its management. In addition to classical diagnostic methods, such as colonoscopy, enteroscopy, angiography or radionucleotide scanning, several other methods have emerged recently, e.g. capsule endoscopy, angiography in combination with methylene blue application and angio-CT, all of them enabling to identify the source of the bleeding. Although conservative therapeutical methods have advanced considerably, the bleeding relapse rates remain high. Surgical intervention is essential in unstable patients with massive bleeding and is frequently applied in patients with relapsing bleeding. The surgical treatment results with respect to postoperative mortality rates and to bleeding relapse rates and to relapse rates of the disorder itself, are very good. The haemorrhaging form of the Crohn’s disease is considered a specific phenotype prone to relapses of bleeding, although in other Crohn’s disease patients the massive bleeding does not occur during the course of the disease.

Klíčová slova:
Crohn‘s disease – acute bleeding