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PLOS Genetics - Číslo 11/2014

Review

32767
Regularized Machine Learning in the Genetic Prediction of Complex Traits

Formal Comment

32767
Establishing a Multidisciplinary Context for Modeling 3D Facial Shape from DNA
Let's Face It—Complex Traits Are Just Not That Simple
Glutamate Receptor Gene , Coffee, and Parkinson Disease
Lack of Replication of the -by-Coffee Interaction in Parkinson Disease

Interview

32767
The Ethics of Our Inquiry: An Interview with Hank Greely

Research Article

32767
RNA Processing Factors Swd2.2 and Sen1 Antagonize RNA Pol III-Dependent Transcription and the Localization of Condensin at Pol III Genes
Inversion of the Chromosomal Region between Two Mating Type Loci Switches the Mating Type in
A Thermolabile Aldolase A Mutant Causes Fever-Induced Recurrent Rhabdomyolysis without Hemolytic Anemia
The Role of Regulatory Evolution in Maize Domestication
Stress Granule-Defective Mutants Deregulate Stress Responsive Transcripts
24-Hour Rhythms of DNA Methylation and Their Relation with Rhythms of RNA Expression in the Human Dorsolateral Prefrontal Cortex
Pseudoautosomal Region 1 Length Polymorphism in the Human Population
Fungal Communication Requires the MAK-2 Pathway Elements STE-20 and RAS-2, the NRC-1 Adapter STE-50 and the MAP Kinase Scaffold HAM-5
The COP9 Signalosome Converts Temporal Hormone Signaling to Spatial Restriction on Neural Competence
The Protein -glucosyltransferase Rumi Modifies Eyes Shut to Promote Rhabdomere Separation in
The Talin Head Domain Reinforces Integrin-Mediated Adhesion by Promoting Adhesion Complex Stability and Clustering
Quantitative Genetics of CTCF Binding Reveal Local Sequence Effects and Different Modes of X-Chromosome Association
Coordinate Regulation of Stem Cell Competition by Slit-Robo and JAK-STAT Signaling in the Testis
Genetic Analysis of a Novel Tubulin Mutation That Redirects Synaptic Vesicle Targeting and Causes Neurite Degeneration in
A Systems Genetics Approach Identifies , , and as Novel Aggressive Prostate Cancer Susceptibility Genes
Three RNA Binding Proteins Form a Complex to Promote Differentiation of Germline Stem Cell Lineage in
Approximation to the Distribution of Fitness Effects across Functional Categories in Human Segregating Polymorphisms
The CSN/COP9 Signalosome Regulates Synaptonemal Complex Assembly during Meiotic Prophase I of
SAS-1 Is a C2 Domain Protein Critical for Centriole Integrity in
An RNA-Seq Screen of the Antenna Identifies a Transporter Necessary for Ammonia Detection
GPA: A Statistical Approach to Prioritizing GWAS Results by Integrating Pleiotropy and Annotation
The Red Queen Model of Recombination Hotspots Evolution in the Light of Archaic and Modern Human Genomes
Functional Diversity of Carbohydrate-Active Enzymes Enabling a Bacterium to Ferment Plant Biomass
Phylogenetically Driven Sequencing of Extremely Halophilic Archaea Reveals Strategies for Static and Dynamic Osmo-response
Natural Polymorphisms in Human APOBEC3H and HIV-1 Vif Combine in Primary T Lymphocytes to Affect Viral G-to-A Mutation Levels and Infectivity
A Germline Polymorphism of Thymine DNA Glycosylase Induces Genomic Instability and Cellular Transformation
Heat-Induced Release of Epigenetic Silencing Reveals the Concealed Role of an Imprinted Plant Gene
ATPase-Independent Type-III Protein Secretion in
p53- and ERK7-Dependent Ribosome Surveillance Response Regulates Insulin-Like Peptide Secretion
The Complex I Subunit Selectively Rescues Mutants through a Mechanism Independent of Mitophagy
Evolution of DNA Methylation Patterns in the Brassicaceae is Driven by Differences in Genome Organization
Regulation of mRNA Abundance by Polypyrimidine Tract-Binding Protein-Controlled Alternate 5′ Splice Site Choice
Systematic Comparison of the Effects of Alpha-synuclein Mutations on Its Oligomerization and Aggregation
Rad59-Facilitated Acquisition of Y′ Elements by Short Telomeres Delays the Onset of Senescence
A Functional Portrait of Med7 and the Mediator Complex in
Systematic Analysis of the Role of RNA-Binding Proteins in the Regulation of RNA Stability
ARTIST: High-Resolution Genome-Wide Assessment of Fitness Using Transposon-Insertion Sequencing
Genomic Evidence of Rapid and Stable Adaptive Oscillations over Seasonal Time Scales in Drosophila
Genome-Wide Associations between Genetic and Epigenetic Variation Influence mRNA Expression and Insulin Secretion in Human Pancreatic Islets
HAM-5 Functions As a MAP Kinase Scaffold during Cell Fusion in

PLOS Genetics

2014 Číslo 11
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