Deficiency of Alpha-1-Antitrypsin
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To what extent does the delay between symptom onset and diagnosis of AATD affect patient survival?
The risk of chronic obstructive pulmonary disease (COPD) is increased, among other things, by a deficiency of alpha-1-antitrypsin (AATD). However, there is often a delay between the onset of symptoms and the diagnosis of AATD, which is associated with worse clinical and functional status and a more advanced stage of the disease. The study presented below examined how this fact further affects patient survival.

Augmentation Therapy of Bronchiectasis Due to AATD – Case Report
Alpha-1-antitrypsin deficiency (AATD) is a rare cause of bronchiectasis unrelated to cystic fibrosis....

Characteristics of Patients with Alpha-1 Antitrypsin Deficiency – Two-Year Data from the EARCO Registry
The international registry of individuals with alpha-1 antitrypsin deficiency (AATD) named EARCO…
Articles on this topic

Alpha-1 Antitrypsin Deficiency and Lung Disease in Patients with Primary Immunodeficiencies
Alpha-1 antitrypsin deficiency (AATD) plays a significant role in the pathogenesis of…

Alpha-1-Antitrypsin Deficiency and Its Association with Atopy in Asthmatics
Literature mentions the coincidence of asthma and alpha-1-antitrypsin deficiency, which is…

Antiviral and Anti-inflammatory Effects of Alpha-1-Antitrypsin in the Treatment of COVID-19
Human alpha-1-antitrypsin (AAT) is a circulating blood glycoprotein that has been used for…

European Registry of Patients with Alpha-1 Antitrypsin Deficiency EARCO Enrolls Patients
Insufficient identification of patients with alpha-1 antitrypsin deficiency (AATD) and a lack…

Can alpha-1-antitrypsin deficiency affect severity and higher mortality in COVID-19 patients?
Alpha-1-antitrypsin (AAT) deficiency is commonly found in the European population. The most…

Quantitative CT as a New Tool for Evaluating COPD in Alpha-1 Antitrypsin Deficiency
For such a rare hereditary disorder as alpha-1 antitrypsin deficiency (AATD), we have so far…

Long-term results of alpha-1-antitrypsin deficiency treatment – RAPID program
RAPID/RAPID Extension is the largest clinical program to date that has confirmed the benefit…

How Common is Alpha-1 Antitrypsin Deficiency?
What is the prevalence of alpha-1 antitrypsin deficiency (AATD)? What comorbidities are…

Impact of Alpha-1 Antitrypsin Deficiency on Quality of Life and Mental Health of Patients
The clinical manifestation of alpha-1 antitrypsin deficiency and its impact on quality of life…

Self-administration of alpha-1-antitrypsin can significantly improve patients' quality of life
Treatment of alpha-1 antitrypsin deficiency (AATD) requires lifetime administration of weekly…
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Most read on this topic
- Autoimmune Liver Diseases in Children. Part I
- Liver disease at alpha-1-antitrypsin deficiency
- Autoimmune liver diseases in children. Part II
- Rare diseases in the year 2019 – the Czech and international context
- Quantitative CT as a New Tool for Evaluating COPD in Alpha-1 Antitrypsin Deficiency
- Current (and Future) Possibilities for Diagnosing Alpha-1-Antitrypsin Deficiency
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