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Biological Treatment

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Good news for sleep in patients with axial spondyloarthritis – ixekizumab effectively reduces night-time back pain

14. 11. 2022 Source: Biological Treatment

The targeted treatment of axial spondyloarthritis currently relies on the anti-inflammatory effects of tumor necrosis factor (TNF) inhibitors, interleukin IL-17 inhibitors, and Janus kinase (JAK) inhibitors. Besides the objective efficacy of these targeted treatments, it is crucial to describe their influence on subjective symptoms for decision-making in clinical practice. The evaluation of the analgesic effect of ixekizumab (IXE) was provided by the randomized controlled trial COAST-V.

atopická dermatitida_dítě

New Therapeutic Options in Light of Current Knowledge on the Pathogenesis of Atopic Dermatitis

Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by intense itching and…
14. 11. 2022 Source: Biological Treatment
Alopecia

Alopecia Areata – Autoimmune Inflammatory Disease and a New Targeted Treatment Option

Alopecia areata (AA) is one of the non-scarring focal alopecias. It is an autoimmune disease of the…
31. 10. 2022 Source: Biological Treatment

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Safety Analysis of Baricitinib in Long-Term Treatment of Rheumatoid Arthritis

Janus kinase inhibitors are relatively new and very promising drugs, but their novelty also…
21. 8. 2020 Source: Biological Treatment
Zlepšení ložiskové psoriázy

Ixekizumab administered for 5 years demonstrated high efficacy and a favorable safety profile in patients with moderate to severe psoriasis

Ixekizumab is a recombinant humanized monoclonal antibody against interleukin 17A, indicated…
19. 5. 2020 Source: Biological Treatment
Ruka a prsty s psoriázou u psoriatické artrititidy

Comparison of Efficacy of Ixekizumab and Adalimumab in Patients with Psoriatic Arthritis and Moderate to Severe Psoriasis

Ixekizumab, a humanized monoclonal antibody against interleukin 17A (IL-17A), is approved in…
9. 5. 2020 Source: Biological Treatment

Direct Comparison of Ixekizumab and Adalimumab in Patients with Psoriatic Arthritis

The final results of the direct comparison of ixekizumab and adalimumab in the therapy of…
6. 4. 2020 Source: Biological Treatment

How do IL-17 and IL-23 inhibitors fare in the treatment of psoriasis in direct comparison?

A recent study published in the British Journal of Dermatology is only the second paper to…
3. 4. 2020 Source: Biological Treatment
Starší žena má zdeformované ruce kvůli revmatoidní artritidě

Therapy Change from Adalimumab to Baricitinib in Patients with Rheumatoid Arthritis

The aim of the presented analysis of data from the RA-BEAM study was to evaluate the clinical…
30. 3. 2020 Source: Biological Treatment
Psoriáza na těle pacienta

Persistence of Treatment with Secukinumab and Ixekizumab in Patients with Moderate to Severe Psoriasis

Although IL-17 targeted drugs are increasingly used in the treatment of moderate to severe…
21. 2. 2020 Source: Biological Treatment
Veselí důchodci tančí v parku

Pain Relief and Functional Score Improvement in Patients with Low Rheumatoid Arthritis Activity: Baricitinib vs. Adalimumab

In patients with rheumatoid arthritis, pain and functional impairment may persist even with…
20. 2. 2020 Source: Biological Treatment

Efficacy and Speed of Pain Relief in Rheumatoid Arthritis When Adding Baricitinib to Methotrexate

The phase III clinical trial RA-BEAM conducted in patients with rheumatoid arthritis (RA)…
17. 2. 2020 Source: Biological Treatment

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