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Development of medicamentous therapy of ED – past, present and future


Authors: V. Vyhnánková;  D. Pacík;  A. Čermák
Authors‘ workplace: Urologická klinika FN Brno a LF MU
Published in: Urol List 2014; 12(1): 19-23

Overview

Modern treatment of erectile dysfunction consists mainly of PDE5 inhibitors as the drugs of first choice. They are the easiest to administer with a quick effect. This includes sildenafil (Viagra), tadalafil (Cialis), vardenafil (Levitra) and avanafil (Stendra). Second‑line therapy includes intracavernous or intra­urethral submission of prostaglandin. Other modern methods, such as gene therapy, are also promising, but further studies are needed for their validation and application in practice.

Key words:
erectile dysfunction, PDE5 inhibitors, PGE1 prostaglandin


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