Toxoplasma and immunodeficiency
Authors:
A. Obr 1; T. Papajík 1; R. Urbanová 1; K. Indrák 1; E. Buriánková 2; J. Ptáček 2
Authors‘ workplace:
Hemato-onkologická klinika LF UP a Fakultní nemocnice Olomouc
1; Klinika nukleární medicíny LF UP a Fakultní nemocnice Olomouc
2
Published in:
Transfuze Hematol. dnes,20, 2014, No. 1, p. 13-18.
Category:
Comprehensive Reports, Original Papers, Case Reports
Overview
We describe case of 34-year old man after autologous stem cell transplantation. He was examined because of fever, progression of right tonsil size, cervical lymphadenopathy, cough, neck pain, dyspnoea about 4 months after transfer of stem cells. Progressively movement dysfunction of right upper limb, urine retention, organic brain syndrome with attacks of somnolence alternate with attacks of anxiety were developed. On whole body PET/CT scan was accumulation of FDG in irregular condensations in both lung sides. Results of cultivation from peripheral blood and BAL were negative repetitively. Two demyelinating lesions were described on MRI of brain. PCR positivity of Toxoplasma was proved in cerebrospinal fluid. Extinction of aliments and health of the patient was improving during targeted antitoxoplasmic therapy. Nowadays, almost 6 years after stem cell transplantation, patient is still in complete remission of lymphoma without any consequence of toxoplasmic infection.
Key words:
toxoplasmosis, immunodeficiency, autologous stem cell transplantation
Sources
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Labels
Haematology Internal medicine Clinical oncologyArticle was published in
Transfusion and Haematology Today
2014 Issue 1
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