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Clinical aspects of „true“ non-secretory multiple myeloma


Authors: T. Pika 1;  P. Lochman 2;  P. Flodr 3;  P. Mičková 4;  M. Novák 4;  Z. Jehlíková 5;  A. Hamplová 6;  J. Minařík 1;  J. Bačovský 1;  L. Kučerová 3;  M. Jarošová 4;  V. Ščudla 1
Authors‘ workplace: III. interní klinika – nefrologická, revmatologická, endokrinologická, LF UP a FN Olomouc 1;  Oddělení klinické biochemie, FN Olomouc, 3Ústav klinické a molekulární patologie, LF UP a FN Olomouc, 4Hematoonkologická klinika, LF UP a FN Olomouc, 5Hematologická ambulance, Šumperská Nemocnice a. s., 6Hematologická ambulance, Nemocnice Šternberk 2
Published in: Transfuze Hematol. dnes,19, 2013, No. 1, p. 27-32.
Category: Comprehensive Reports, Original Papers, Case Reports

Overview

Non-secretory myeloma represents a less frequent variant of multiple myeloma. The development of electrophoretical methods and especially serum free light chain assessment has enabled the identification of secretion in patients formerly classified as non-secretory disease. Therefore, „true“ non-secretory myeloma defines a very rare condition, with typical biological-genetic characteristics, which requires a very specific diagnostic and therapeutic approach.

Key words:
multiple myeloma, non-secretory myeloma


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