Changes of the Mean Platelet Volume during Body WeightReduction
Authors:
R. Malý 1; H. Malá 2; M. Pecka 3
Authors‘ workplace:
I. interní klinika LF UK a FN, Hradec Králové 2Gerontologická a metabolická klinika FN, Hradec Králové 3II. interní klinika FN, Hradec Králové
1
Published in:
Transfuze Hematol. dnes,, 2003, No. 1, p. 48-51.
Category:
Overview
Blood platelets play a central role in the physiology of primary haemostasis and in the pathophysiologicalprocesses of arterial thrombosis. Since the platelet volume reflects platelet activity, the meanplatelet volume (MPV) is a further independent risk factor for cardiovascular disease. Although it iswell established that weight reduction reduces some risk factors of cardiovascular disease in obesepatients, an increase of MPV occurs during the period of weight loss. In two groups of 46 obese patients(the first group of 24 patients with short-term modified fasting, the second of 22 patients with a verylow calorie diet) the authors confirmed the effect of modified fasting and a low calorie diet on the bodyweight and body mass index. They also proved in both groups a major decrease of cholesterol values(p
Key words:
mean platelet volume (MPV), body weight reduction,modified fasting, very low calorie diet
Labels
Haematology Internal medicine Clinical oncologyArticle was published in
Transfusion and Haematology Today
2003 Issue 1
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