Monoclonal Antibody Therapy in Haematological Malignancies

Czech version

Authors: P. Klener
Authors‘ workplace: 1. interní klinika VFN a Ústav hematologie a krevní transfuze, Praha
Published in: Transfuze Hematol. dnes,, 2002, No. 4, p. 0.
Category:

Overview

Monoclonal antibody (MAbs) therapy has emerged as a viable treatment option for patients in haematologicalmalignancies. Clinical use ofMAbs has been facilitated by recombinantDNAtechnology,whichhas been used to engineer chimeric and humanized MAbs. They can be used as „naked MAbs“, orconjugated (with toxin, radioisotope, or with cytotoxic drug). The author reviews different MAbs usedin clinical practice, or studied in clinical trials.

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Labels

Haematology Internal medicine Clinical oncology

Article was published in

Transfusion and Haematology Today

2002 Issue 4