Adenocarcinoma in situ of the uterine cervix – analysis of 10 cases
Authors:
P. Freitag; J. Sláma
Authors‘ workplace:
Gynekologicko‑porodnická klinika 1. LF UK a VFN v Praze
Published in:
Prakt Gyn 2009; 13(2): 76-78
Overview
In a series of 10 cases of adenocarcinoma in situ of the uterine cervix, age of patients, parity, contraception, cytological, colposcopical and histological findings, operations and definitive solutions have been analysed. Median age was 37 (24–75), 4 patients were nulligravidae and 4 were hormonal contraception users. Praebioptic suspicion of a glandular laesion was expressed in 3 cases (twice by colposcopy, twice by cytology). In 9 patients the coexistent squamous laesion was concurrently present. In 7 cases histologically positive margins were described and in all these patients repeated or definitive operations were performed.
Key words:
adenocarcinoma in situ – uterine cervix – colposcopy – cytology – positive margins
Sources
1. Sláma J, Freitag P, Cibula D et al. Adenoprekancerózy děložního hrdla. Čes Gynek 2006; 17(6): 446–450.
2. Salani R, Puri I, Bristow RE. Adenocarcinoma in situ of the uterine cervix: a metaanalysis of 1278 patients evaluating the predictive value of conization margin status. Am J Obstet Gynecol 2008; Nov 17. [Epub ahead of print].
3. Dedecker F, Graesslin O, Bonneau S et al. Persistence and recurrence of in situ cervical adenocarcinoma after primary treatment. Gynecol Obstet Fertil 2008; 36(6): 616–622.
4. Young JL, Jazaeri AA, Lachance JA et al. Cervical adenocarcinoma in situ: the predictive value of conization margin status. Am J Obstet Gynecol 2007; 197(2): 195.
5. Bull-Phelps SL, Garner EI, Walsh CS et al. Fertility sparing surgery in 101 women with adenocarcinoma in situ of the cervix. Gynecol Oncol 2007; 107(2): 316–319.
6. Dalrymple C, Valmadre S, Cook A et al. Cold knife versus laser cone biopsy for adenocarcinoma in situ of the cervix – a comparison of management and outcome. Int J Gynecol Cancer 2008; 18(1): 116–120.
7. Graesslin O, Dedecker F, Collinet P et al. Management of in situ cervical adenocarcinoma. Gynecol Obstet Fertil 2006; 34(12): 1178–1184.
8. Hwang DM, Lickrish GM, Chapman W et al. Long‑term surveillance is required for all women treated for cervical adenocarcinoma in situ. J Low Genit Tract Dis 2004; 8(2): 125–131.
Labels
Paediatric gynaecology Gynaecology and obstetrics Reproduction medicineArticle was published in
Practical Gynecology
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