The unexplainable fever syndrome in adolescence
Authors:
M. Kliment; P. Kertys 1; D. Červenková 2
Authors‘ workplace:
Gynekologicko-pôrodnícka klinika, Slovenská zdravotnícka univerzita, Bratislava
; Oddelenie klinickej imunológie FN Bratislava
1; Dermatoalergologická ambulancia, Poliklinika Ružinov, Bratislava
2
Published in:
Prakt Gyn 2005; 9(4): 8-10
Overview
The authors inform about the clinical syndrome, lately described and less known in gynecological community, manifested by the attacks of febrilities, often connected with abdominal symptomatology, which is standardly accompanied by increased IgD serum level. In casuistics they describe their experience with similarly progressing disease in young patient. Nowadays, they consult the case, based on existing laboratory examinations as well as the clinical course, with international working group at University in Dutch Nijmegene “International Hyper-IgD study group”, engaged in this relatively rare disease.
Key words:
unexplainable fevers in adolescence – hyperimmunoglobulinemia – mevalonate kinase enzyme deficiency – International Hyper-IgD study group
Sources
1. Kliment M, Červenková D, Kertys P. Niektoré aspekty recidivujúcich vulvovaginitíd. Terapia 2004; 4: 27-30.
2. Van der Meer JWM, Vossen JM, Radl J, Van Nieuwkoop JA, Meijer CJLM, Lobatto S, Van Furth R. Hyperimmunoglobulinemia D and periodic fever: a new syndrome. Lancet 1984; 1(8386): 1087-1090.
3. Reeves WG, Mitchell JRA. Hyperimmunoglobulinemia D and periodic fever. Lancet 1984; i: 1463-1464.
4. Scolozzi R, Boccafogli A, Vicentini L, Dell'acqua G, Traniello S, Spinasi S, Salmi R, Coletti M, Lanza M, Lanza F, Pansini R. Recurrent fever associated with serum hyper-IgD and inverted kappa/lambda ratio in the lymphocyte surface IgD. Immunol Clin Sper 1985; 4: 269-276.
5. Prieur AM, Griscelli Cl. Aspect nosologique des formes systémiques d'arthrite juvénile à début très précoce. A propos de dix-sept observations. Ann Pédiat 1983; 30: 565-569.
6. Frenkel J, Houten SM, Waterham HR, Wanders RJA, Rijkers GT, Duran M, Kuijpers TW, van Luijk W et al. Clinical and molecular variability in childhood periodic fever with hyperimunoglobulinemia D. Rheumatology 2001; 40: 579-584.
Labels
Paediatric gynaecology Gynaecology and obstetrics Reproduction medicineArticle was published in
Practical Gynecology
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