Laparoscopic versus open left pancreatectomy: surgical stress response comparison in the porcine model
Authors:
Radek Pohnán 1; M. Ryska 1; J. Kalvach 1; L. Hána 1; T. Henlín 2; J. Pejchal 3
Authors‘ workplace:
Chirurgická klinika, 2. Lékařská fakulta Univerzity Karlovy a ÚVN, Praha
1; Klinika anesteziologie, resuscitace a intenzivní medicíny, 1. Lékařská fakulta Univerzity Karlovy a ÚVN
2; Katedra toxikologie a vojenské farmacie, Fakulta vojenského zdravotnictví, Univerzita obrany
3
Published in:
Rozhl. Chir., 2018, roč. 97, č. 5, s. 234-238.
Category:
Original articles
Overview
Introduction:
Although several techniques of laparoscopic left pancreatectomy have already been developed through experiments on animals and human patients, there is still insufficient information about their pathophysiological mechanisms, especially the impact on surgical stress.
Method:
In a group of 10 pigs, open left pancreatectomy was performed, and the other group of 10 pigs underwent laparoscopic left pancreatectomy. Postoperative stress was compared by determining serum levels of leukocytes, interleukin 1, 6 and CRP from peripheral venous blood collection. The blood was collected prior to incision, 1 and 2 hours after incision, 24 hours after the beginning of the procedure, and on the 7th postoperative day.
Results:
No statistically significant difference was found between open and laparoscopic left pancreatectomy in the measured values of leukocytes, IL-1 and 6 and CRP.
Key words:
laparoscopy – left pancreatectomy − surgical stress response − interleukin 1 − interleukin 6
Sources
Literatura
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Surgery Orthopaedics Trauma surgeryArticle was published in
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