Risk of Colorectal Carcinoma in a Patient with Ulcerative Colitis
Authors:
I. Klementa; P. Skalický; K. Vysloužil; L. Starý; P. Zbořil; K. Vomáčková; B. Klementa *; M. Konečný **
Authors‘ workplace:
I. chirurgická klinika FN Olomouc, přednosta: doc. MUDr. Čestmír Neoral, CSc.
; Klinika anesteziologie a resuscitace FN Olomouc, přednosta: MUDr. Jan Neiser
*; II. interní klinika FN Olomouc, přednosta: doc. MUDr. Vlastimil Procházka, Ph. D.
**
Published in:
Rozhl. Chir., 2010, roč. 89, č. 12, s. 754-759.
Category:
Monothematic special - Original
Overview
Colorectal cancer, in patients with ulcerative colitis, is detected in the resected tissue of approximately 5% of patients, according to the literature. In our set of 82 patients operated on between the years 2000–2009, malignancy was confirmed in 9/82 patients (11%). In two young patients, the peroperative findings showed inoperable generalized carcinoma. The greater incidence of malignity is surely associated with inconsistent dispensarization of these patients.
Key word:
ulcerative colitis – surgery – colorectal cancer
Sources
1. Bernstein, C. N. Natural history and management of flat and polypoid dysplasia in inflammatory bowel disease. Gastroenterol. Clin. North Am., 2006; 35: 573–579.
2. Eaden, J. A., Abrams, K. R., Mayberry, J. F. The risk of colorectal cancer in ulcerative colitis: a meta-analysis. Gut, 2001; 48: 526–535.
3. Eaden, J. A., Mayberry, J. F. Guidelines for screening and surveillance of asymptomatic colorectal cancer in patients with inflammatory bowel disease. Gut, 2002; 51 Suppl 5: V10–V12.
4. Ekbom, A., Helmick, C., Zack, M., Adami, H. O. Ulcerative colitis and colorectal cancer. A population-based study. N. Engl. J. Med., 1990; 323: 1228–1233.
5. Heuschen, U. A., Hinz, U., Allemeyer, E. H., Autschbach, F., Stern, J., Lucas, M., Herfarth, C., Heuschen, G. Risk factors for ileoanal J pouch-related septic complications in ulcerative colitis and familial adenomatous polyposis. Ann. Surg., 2002; 235: 207–216.
6. Klementa, I., Hrbek, J., Konečný, M., Skalický, P., Neoral, Č. Spolupráce chirurga a radiologa při řešení double stapled ileo-J-pouch-anální anastomózy. Miniinvazívna chirurgia a endoskopia, ročník XI, 2007, 3–4, s. 12–15.
7. Klementa, I., Zbořil, P., Starý, L., Skalický, P., Vomáčková, K., Neoral, Č. Změna fyziologie anorekta po kolektomii s J-rezervoárem pro ulcerózní kolitidu. Miniinvazívna chirurgia a endoskopia, ročník XI, 2007, 1, s. 5–8.
8. Langholz, E., Munkholm, P., Davidsen, M., Binder, V. Colorectal cancer risk and mortality in patients with ulcerative colitis. Gastroenterology, 1992; 103: 1444–1451.
9. Lim, C. H., Dixon, M. F., Vail, A., Forman, D., Lynch, D. A., Axon, A. T. Ten year follow up of ulcerative colitis patients with and without low grade dysplasia. Gut, 2003; 52: 1127–1132.
10. Nuako, K. W., Ahlquist, D. A., Mahoney, D. W., Schaid, D. J., Siena, D. M., Lindor, N. M. Familial predisposition for colorectal cancer in chronic ulcerative colitis: a case-control study. Gastroenterology, 1998; 115: 1079–1083.
11. Odze, R. D., Farraye, F. A., Hecht, J. L., Hornick, J. L. Long-term follow-up after polypectomy treatment for adenoma-like dysplastic lesions in ulcerative colitis. Clin. Gastroenterol. Hepatol., 2004; 2: 534–541.
12. Parks, A. G., Nicholls, R. J. Proctocolectomy without ileostomy for ulcerative colitis. Br. Med. J., 1978; 2: 85–88.
13. Rodriguez-Sanjuan, J. C., Polavieja, M. G., Naranjo, A., Castillo. J. Adenocarcinoma in an ileal pouch for ulcerative colitis. Dis. Colon Rectum, 1995; 38: 779–780.
14. Rubio, C. A., Nefrite, R., Ljung, T., Jaramillo, E., Slezak, P. Colorectal carcinoma in ulcerative colitis is decreasing in Scandinavian countries. Anticancer Res., 2001; 21: 2921–2924.
15. Rutter, M., Saunders, B., Wilkinson, K., Rumbles, S., Schofield, G., Kamm, M., Williams, C., Price, A., Talbot, I., Forbes, A. Severity of inflammation is a risk factor for colorectal neoplasia in ulcerative colitis. Gastroenterology, 2004; 126: 451–459.
16. Rutter, M. D., Saunders, B. P., Schofield, G., Forbes, A., Price, A. B., Talbot, I. C. Pancolonic indigo carmine dye spraying for the detection of dysplasia in ulcerative colitis. Gut, 2004; 53: 256–260.
17. Rutter, M. D., Saunders, B. P., Wilkinson, K. H., Rumbles, S., Schofield, G., Kamm, M. A., Williams, C. B., Price, A. B., Talbot, I. C., Forbes, A. Thirty-year analysis of a colonoscopic surveillance program for neoplasia in ulcerative colitis. Gastroenterology, 2006; 130: 1030–1038.
18. Soetikno, R. M., Lin, O. S., Heidenreich, P. A., Young, H. S., Blackstone, M. O. Increased risk of colorectal neoplasia in patients with primary sclerosing cholangitis and ulcerative colitis: a metaanalysis. Gastrointest. Endosc., 2002; 56: 48–54.
19. Vysloužil, K., Konečný, M., Albín, A., Klementa, I., Travěncová, I. Chirurgické možnosti léčení ulcerózní kolitidy. Rozhl. Chir., 1997; 10: 514–517.
20. Vysloužil, K., Králík, J., Gregar, I., Zmrzlík, P. Chirurgická léčba akutních komplikací idiopatické ulcerózní kolitidy. Čs. gastroenterol. a výž., 1993; 47: 128–131.
Labels
Surgery Orthopaedics Trauma surgeryArticle was published in
Perspectives in Surgery
2010 Issue 12
Most read in this issue
- Rare Umbilical Anomalies
- Ambulatory Excision of Perianal Duplicatures
- Solitary Fibrous Tumor of Pleural Cavity
- XLIF – A New Technique of the Lumbar Vertebra Replacement: Initial Experience