Kawasaki Syndrome – Possible Cause of Cervical Lymphadenitis in Children
Authors:
H. Jelínková 1,2; I. Bártová 1; V. Němec 3
Authors‘ workplace:
Klinika ORL a chirurgie hlavy a krku, Pardubická krajská nemocnice, a. s.
; přednosta prof. MUDr. V. Chrobok, CSc., Ph. D.
Fakulta zdravotnických studií, Univerzita Pardubice
1; děkan prof. MUDr. A. Pellant, DrSc.
Dětské a novorozenecké oddělení, Pardubická krajská nemocnice, a. s.
2; primář MUDr. V. Němec, Ph. D.
3
Published in:
Otorinolaryngol Foniatr, 59, 2010, No. 4, pp. 202-208.
Category:
Original Article
Overview
Cervical lymphonoditis is a common event in childhood. In differential diagnostic protocol Kawasaki syndrome (KS) should be considered. The diagnosis of Kawasaki disease is based on presence of diagnostic criteria (dominant symptoms): fever, cervical lymphonoditis, conjunctivitis, stomatitis, skin lesions of palm and sole and red rush. These common nonspecific symptoms have features that are typical for KS. Early diagnosis and onset of treatment (intravenous imunoglobulin administration) prevent from development of coronary complications that could have fatal sequel. We bring a detailed description of the clinical of KS and two case reports.
Key words:
Kawasaki disease (syndrome), vasculitis, coronary aneurysm, fever, exanthema in children, cervical lymphonoditis (lymfadenitis), conjunctivitis, aseptic meningitis, infectious mononucleosis, strawberry tongue, imunoglobuline, infliximab
Sources
1. Brogan, P. A. et al: Kawasaki disease: an evidence based approach to diagnosis, treatment, and proposals for future research. Arch. Dis. Child, 86, 2002, s. 286-290.
2. Burns, J. C. et al: Kawasaki disease: A brief history. Pediatrics, 106, 2000, 2, s. 27.
3. Burns, J. C., Joffe, L. et al: Anterior uveitis associated with Kawasaki syndrome. Pediatr. Infect Dis., 4, 1985, 3, s. 258-261.
4. Dhillon, R., Clarkson, P. et al: Endothelial dysfunction late after Kawasaki disease. Circulation, 94, 1996, s. 2103-2106.
5. Falcini, F. et al: Kawasaki disease in the third millineum: Syndrome still at risk to be unrecognised or underdiagnosed. Pediatric Rheumatology Online Journal, 2003. Electronic article, Available from:
http://www.pedrheumonlinejournal.org/April/PDF/kawasaki.pdf.
6. Holman, C. R. et al.: Kawasaki syndrome hospitalizations in the United States 1997 and 2000. Pediatrics, 112, 2003, 3, s. 495-501.
7. Cheung, Y. F. et al: Increased high sensitivity C reactive protein concentrations and increased arterial stiffness in children with a history of Kawasaki disease. Heart, 90, 2004, s. 1281-1285.
8. Jehlička, P., Lád, V., Sedláček, D.: Kawasakiho syndrom. Pediatrie pro praxi, 9, 2008, 1, s. 12-14.
9. Jen, M. et al.: Cervical spine and temporomandibular joint arhtritis in a child with Kawasaki disease. 118, 2006, s. 1569-1571.
10. Kawasaki, T.: Pediatric acute febrile mucocutaneous lymph node syndrome with characteristic desquamation of fingers and toes: My clinical observation of fifty cases. Jpn. J. Allergy, 1967. Anglický překlad: Pediatr. Infect. Dis. J., 21, 2002, s. 1-38.
11. Kim, D.: Kawasaki disease. Yonsei Med. J., 47, 2006, 6, s. 759-772.
12. Khubchandani, R.: Kawasaki disease in India. Pediatric Rheumatology Online Journal, 2, 2004, 2.
13. Lee, T. J. et al: Low-dose methotrexate therapy for intravenous immunoglobulin-resistant Kawasaki disease. Yonsei Med. J., 49, 2008, 5, s. 714-718.
14. Pemberton, M. N.: Case study: Recurrent Kawasaki disease. Britis Dental Journal., 186, 1999, s. 270-271.
15. Rowley, A. H., Shulman, S. T.: Kawasaki syndrom. Clin. Microbiol. Rev., 11, 1998, 3, s. 405-414.
16. Shibuya, N. et al.: Kawasaki disease before Kawasaki at Tokyo University Hospital. Pediatrics, 110, 2002, s. 17.
17. Singh, R. et al.: Atypical Kawasaki disease and gastrointestinal manifestations. Paediatr. Child Health, 12, 2007, 3, s. 235-237.
18. Tashiro, N. et al.: Ultrasonographic evaluation of cervical lymph nodes in Kawasaki Disease. Pediatrics, 109, s. 77.
Labels
Audiology Paediatric ENT ENT (Otorhinolaryngology)Article was published in
Otorhinolaryngology and Phoniatrics
2010 Issue 4
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