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Toxic Impairment of the Liver with Trinitrotoluene


Authors: V. Hassmanová 1;  P. Hůlek 2;  J. Nožička 3
Authors‘ workplace: Klinika nemocí z povolání UK Praha, Lékařská fakulta a Fakultní nemocnice Hradec Králové, zastupující přednosta MUDr. Eva Korolová 2I. interní klinika UK Praha, Lékařská fakulta a Fakultní nemocnice Hradec Králové, přednosta doc. MUDr. Miloslav Pleskot, C 1
Published in: Pracov. Lék., , 2002, No. 4, s. 186-189.
Category:

Overview

The paper reports non-alcoholic steatohepatitis (NASH) in a 55-year-old man who worked for 22 years under a significanttrinitrotoluene risk. The found disease is an example of the fact that non too significant pathological laboratory findings can beaccompanied by a serious histological picture showing not only liver steatosis, with contributing concurrent hyperlipoproteinaemia,but primarily showing marked necrotic-inflammatory changes. A sporadic finding of Mallory’s hyaline does not exclude theparticipation of alcohol, but certainly there are no sings of alcoholic affection.

Key words:
trinitrotoluene, non-alcoholic steatohepatitis

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Labels
Hygiene and epidemiology Hyperbaric medicine Occupational medicine
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