Stereotactic radiotherapy with CyberKnife added to local therapy of differentiated thyroid cancer
Authors:
M. Havel 1; P. Širůček 1; L. Knybel 2; K. Resová 2; J. Cvek 2; G. Havlová 1; O. Kraft 1; K. Bukovanský 1
Authors‘ workplace:
Klinika nukleární medicíny, FN Ostrava a LF OU
1; Onkologická klinika FN Ostrava a LF OU, ČR
2
Published in:
NuklMed 2023;12:27-31
Category:
Original Article
Overview
Introduction: Stereotactic body radiation therapy (SBRT) is a modern method in external radiation therapy. It offers an option to use a high dose of radiation with a higher biological effect in a small target volume. We assessed the patients with the thyroid cancer indicated to this type of therapeutic approach.
Patients and methods: We evaluated a group of patients with the differentiated thyroid cancer retrospectively, indicated to SBRT for the persisting residuals on the neck, from the time interval 2011–2019.
Results: During the nine years interval, 14 patients (10 female, 4 male), underwent this type of therapy. Radioiodine accumulating remnants were present before SBRT in 9 patients, higher thyroglobulin (Tg) levels or residuals diagnosed by other imaging modalities were indications in 5 patients. The radioiodine accumulating residuals regressed fully or partially in all 9 cases. In the later 5 patients there was not observed any progression on the imaging examinations, response according to the thyroglobulin levels was variable.
Conclusion: SBRT with the robotic CyberKnife system represents another therapeutic modality for patients with differentiated thyroid cancer, allowing local control of the disease.
Keywords:
cyberknife – stereotactic radiotherapy – differentiated thyroid cancer
Sources
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