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Modification of reconstruction parameters of IQ-SPECT study to maintain continuity of left ventricle functional parameters processing results


Authors: Martin Havel 1;  Milan Kamínek 1;  Lenka Henzlová 1;  Pavel Koranda 1;  Otakar Kraft 2;  Kateřina Langová 3
Authors‘ workplace: Klinika nukleární medicíny, LF Univerzity Palackého a Fakultní nemocnice Olomouc 1;  Klinika nukleární medicíny, LF Ostravské univerzity a Fakultní nemocnice Ostrava 2;  Ústav lékařské biofyziky, LF Univerzity Palackého Olomouc 3
Published in: NuklMed 2016;5:66-71
Category: Original Article

Overview

Introduction:
IQ-SPECT system represents the technological effort in myocardial perfusion imaging. However, we observed substantial discrepancies in acquired perfusion and functional parameters of the left ventricle when comparing those from IQ-SPECT and conventional tomographic camera. We tried to find the optimisation of the IQ-SPECT study reconstruction to get minimal differences between the systems concerning the functional parameters of the left ventricle.

Subjects and methods:
The study group consists of 42 patients (27 male, 15 female, mean age 62.3 ± 9.2 years) who underwent gated-SPECT study at rest condition on both systems. The IQ-SPECT data were processed with Flash3D iterative reconstruction algorithm; various settings of Butterworth filter were serially applied. Reconstructed studies were assessed in Corridor4DM application. Values of ejection fraction (EF), end-diastolic and end-systolic volumes (EDV, ESV) of the left ventricle obtained from conventional system were compared with those from initial and filtered IQ-SPECT studies.

Results:
The EF values were systematically higher on conventional system, EDV values were systematically lower, ESV values showed proportional error for the initial setting of IQ-SPECT reconstruction. Lowest absolute differences for EF values were observed for the Butterworth filtering of order 1 and cut-off 0.32. Comparing outcomes from conventional system and such optimised IQ-SPECT study, EF, EDV and ESV showed neither systematic nor proportional error.

Conclusion:
When adopting new method, the reproducibility of the outcomes during the follow-up is essential. With postprocessing of IQ-SPECT study there is possibility to adjust the obtained functional parameters of the left ventricle to achieve minimal and clinically irrelevant differences to conventional tomographic method.

Key words:
IQ-SPECT, conventional SPECT, image processing, functional parameters of left ventricle


Sources

1. Shaw LJ, Iskandrian AE. Prognostic value of gated myocardial perfusion SPECT. J Nucl Cardiol 2004;11:171-185

2. Imbert L, Poussier S, Franken PR et al. Compared performance of high-sensitivity cameras dedicated to myocardial perfusion SPECT: a comprehensive analysis of phantom and human images. J Nucl Med 2012;53:1897-1903

3. DePuey EG. Advances in SPECT camera software and hardware: currently available and new on the horizon. J Nucl Cardiol 2012;19:551-581

4. Havel M, Kolacek M, Kaminek M et al. Myocardial perfusion imaging parameters: IQ-SPECT and conventional SPET system comparison. Hell J Nucl Med 2014;17:200-203

5. Standardy zdravotní péče - národní radiologické standardy - nukleární medicína. Soubor doporučení a návod pro tvorbu místních radiologických postupů (standardů) na diagnostických a terapeutických pracovištích nukleární medicíny v České republice. In Věstník Ministerstva zdravotnictví České republiky 2011.Částka 9. 99-247

6. Henzlova MJ, Duvall WL. The future of SPECT MPI: time and dose reduction. J Nucl Cardiol 2011;4:580-587

7. Slomka PJ, Patton JA, Berman DS et al. Advances in technical aspects of myocardial perfusion SPECT imaging. J Nucl Cardiol 2009;16:255-276

8. Maeder MT, Kaye DM. Heart failure with normal left ventricular ejection fraction. J Am Coll Cardiol 2009;53:905-918

9. Curtis JP, Sokol SI, Wang Y et al. The association of left ventricular ejection fraction, mortality, and cause of death in stable outpatients with heart failure. J Am Coll Cardiol. 2003;42:736-742

10. Foley TA, Mankad SV, Anavekar NS et al. Measuring left ventricular ejection fraction - techniques and potential pitfalls. European Cardiology. 2012;8:108-114

11. Bellenger NG, Burgess MI, Ray SG et al. Comparison of left ventricular ejection fraction and volumes in heart failure by echocardiography, radionuclide ventriculography and cardiovascular magnetic resonance. Are they interchangeable?. Eur Heart J 2000;21:1387-1396

12. Wood PW, Choy JB, Nanda NC et al. Left ventricular ejection fraction and volumes: it depends on the imaging method. Echocardiography 2014;31:87-100

13. Singh RM, Singh BM, Mehta JL. Role of cardiac CTA in estimating left ventricular volumes and ejection fraction. World J Radiol 2014;6: 669–676

14. Navare SM, Wackers FJ, Liu YH. Comparison of 16-frame and 8-frame gated SPET imaging for determination of left ventricular volumes and ejection fraction. Eur J Nucl Med Mol Imaging 2003;30:1330-1337

15. Ather S, Iqbal F, Gulotta J et al. Comparison of three commercially available softwares for measuring left ventricular perfusion and function by gated SPECT myocardial perfusion imaging. J Nucl Cardiol 2014;21:673-681

16. Nakajima K, Higuchi T, Taki J et al. Accuracy of ventricular volume and ejection fraction measured by gated myocardial SPECT: comparison of 4 software programs. J Nucl Med 2001;42:1571-1578

17. Lyon MC, Foster C, Ding X et al. Dose reduction in half-time myocardial perfusion SPECT-CT with multifocal collimation. J Nucl Cardiol 2016;23:657-667

18. Matsutomo N, Akio N, Masayuki S. Performance of myocardial perfusion imaging using multi-focus fan beam collimator with resolution recovery reconstruction in a comparison with conventional SPECT. Asia Ocean J Nucl Med Biol 2014;2:111–119

19. Caobelli F, Pizzocaro C, Paghera B et al. Evaluation of patients with coronary artery disease. IQ-SPECT protocol in myocardial perfusion imaging: Preliminary results. Nuklearmedizin 2013;52:178-185

20. Onishi H, Matsutomo N, Kangai Y et al. Differential impact of multi-focus fan beam collimation with L-mode and conventional systems on the accuracy of myocardial perfusion imaging: Quantitative evaluation using phantoms. Asia Ocean J Nucl Med Biol 2013;1:28-34

21. de Jong AN, Akkermans JBM, Van Asperen EA et al. Left ventricular ejection fraction in gated myocardial perfusion, a comparison of SPECT and IQ-SPECT (P847). Eur J Nucl Med Mol Imaging. 2014;41 Suppl 2:S601

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