The long-term effectivity control of sentinel lymph node biopsy through the follow-up of complex therapy results
Authors:
Milan Šimánek () 1; Václav Abrahám () 2; Jaromír Kořínek () 2
Authors‘ workplace:
Oddělení nukleární medicíny Nemocnice Pelhřimov p. o., ČR
1; Onkologická ambulance Nemocnice Pelhřimov p. o., ČR
2
Published in:
NuklMed 2013;2:13-17
Category:
Original Article
Overview
The aim:
The effectivity evaluation of the sentinel lymph node biopsy and subsequent therapy of the breast carcinoma after the implementation of the method into the clinical practice.
Patients and methods:
From 2006 to 2010, 94 patients with breast carcinoma who underwent the sentinel lymph node biopsy, average age 60,6 years, tumour size up to T2 in TNM classification (85 % T1, 10 % T2,5 % TIS) were included in the follow-up. The sentinel lymph node biopsy was done with the periareolar injection of radiotracers with larger colloid particles. The positive sentinel nodes were found in 27 % of patients, 23 % of which presented by micrometastasis or isolated tumor cells. The axillary dissection was indicated if the sentinel node was positive. The breast irradiation and selectively axilla irradiation were done in 79 %. Subsequently the patients were treated according to the standard protocol and were observed in Oncological Department of the Hospital Pelhrimov. The average follow-up was 3.9 years. The common parameters for evaluation of the oncological patients care were calculated.
Results:
The locoregional recurrence was 1 %, axillary recurrence was 0 %, distant recurrence was 0 %, disease-free survival have reached 99 % and overall survival 99 % of patients.
Conclusion:
The surgery guided by the results of the sentinel node biopsy with the periareolar injection of the radiotracer and combined with radiotherapy in breast cancer patients has appeared as very effective, corresponding to the good locoregional control of disease and with standard therapeutic protocol it provides good overall results of the treatment.
Key words:
breast cancer, sentinel node biopsy, follow-up, recurrences, survival analysis
Sources
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Nuclear medicine Radiodiagnostics RadiotherapyArticle was published in
Nuclear Medicine
2013 Issue 1
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