Serum concentration and tubular resorption of sodium and chloride in patients with chronic renal disease
Authors:
Otto Schück 1,2; Miroslava Horáčková 1; Vladimír Teplan 2; Hana Malinská 2; Milena Štolová 2; Irena Látová 2; Jana Urbanová 2
Authors‘ workplace:
Interní klinika 2. LF UK, Praha
1; Institut klinické a experimentální medicíny, Praha
2
Published in:
Čas. Lék. čes. 2015; 154: 236-238
Category:
Original Article
Overview
Tubular transport of sodium (TNa+) and chloride (TCl–) is decreased in patients with chronic kidney disease. The decrease of TCl– is relatively lower than that of TNa+. These changes of tubular transport of Na+ and Cl– participate on the development of acid base disturbance in patients with chronic kidney disease and with their glomerular filtration rate lower than 0.5 ml/s/1.73 m2.
Keywords:
sodium – chloride – kidney – tubular reabsorption
Sources
1. Nagasha D, Nassar jr AP, Maciel AT, et al. The use of sodium-chloride difference surrogates in the evaluation of metabolic acidosis in critically ill patients. J Crit Care 2010; 25: 525–531.
2. Kurt A, Ecevit A, Ozkiraz S, et al. The use of chloride-sodium ratio in the evaluation of metabolic acidosis in critically ill neonates. Eur J Pediatr 2012; 171: 963–969.
3. Story DA, Morimatsu H, Bellamo R, et al. Strong ions, weak acids and base excess: a simplified Fencl-Stewart approach to clinical acid-base disorders. Br J Anesth 2004; 92: 54–60.
4. Story DA, Tosolini A, Bellamo R, et al. Plasma acid-base changes in chronical renal failure: a Stewart analysis. Int J Artif Organs 2005; 28: 961–965.
5. Fencl V, Leith DE. Stewart’s quantitative acid-base chemistry: Applications in biology and medicine. Respir Physiol 1993; 91: 1–16.
6. Klaboch J, Opatrná S, Matoušovic K, et al. Acid-base balance in peritoneal dialysis patients: a Stewart-Fencl analysis. Renal Failure 2009; 31: 625–632.
7. Havlín J, Matoušovic K, Schück O, et al. Patofyziologie vzniku metabolické acidózy u pacientů se sníženou glomerulární filtrací z hlediska Stewartovy-Fenclovy teorie. Vnitř. Lék. 2009; 55: 97–104.
8. Opatrná S, Matoušovic K, Klaboch J, et al. Importance of serum (Na+) and (Cl–) difference in acid,base classification. Anesth Analg 2010; 111: 243–244.
9. KDIGO 2012 Clinical Practice Guidelines for Evacuation and Management of Chronic Kidney Disease. Kidney Int 2013; Suppl 3: 1–150.
10. Schück O. Examination of kidney function. Boston – Hague – Dordrecht – Lancastrer: Martinus Nijhoff Publishers 1984.
11. White RP, Samson FE. Determination of inulin by use of anthrone. J Lab Clin Med 1954; 43: 475–478.
12. Fencl V, Jabor A, Kazda A, et al. Diagnosis of metabolic acid-base disturbances in critically ill patients. Am J Resp Crit Care Med 2000; 162: 2246–2251.
13. Halperin M, Goldstein MB. Fluid, Electrolyte and Acid Base Physiology 3rd ed. Philadelphia: WB Saunders Comp. 1999.
14. Jabor A a kol. Vnitřní prostředí. Praha: Grada Publishing 2008.
Labels
Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain management Dental HygienistArticle was published in
Journal of Czech Physicians
Most read in this issue
- New psychoactive substances and their prevalence in the Czech Republic
- Ultrasound elastography and its use in the head and neck imaging
- The Cryopre-servation: history and the ethical issue of storing embryos
- Pharmaconutrition in intensive and perioperative care