New options for therapeutic revascularization in lower extremity limb ischemia linked to the diabetic foot syndrome by autologous stem cell transplantation
Authors:
Jakub Svěcený 1; Eva Syková 2; Michal Tichý 3; Jiří Laštůvka 1
Authors‘ workplace:
Všeobecná interna, Krajská zdravotní, a. s. – Masarykova nemocnice v Ústí nad Labem, o. z.
1; Ústav experimentální medicíny AV ČR, v. v. i.
2; Gastroenterologické oddělení, Krajská zdravotní, a. s. – Masarykova nemocnice v Ústí nad Labem, o. z.
3
Published in:
Čas. Lék. čes. 2015; 154: 161-167
Category:
Review Article
Overview
Type 2 diabetes incidence is growing worldwide. It is in up to 50% cases linked with diabetic foot syndrome. This is associated with peripheral neuropathy and peripheral artery disease which increases risk of defects with impaired healing. Resulting high number of amputations has major influence on the quality of life and constitutes serious clinical issue. In recent years numerous clinical studies have shown positive effect of new treatment modality using regenerative potential of the autologous stem cells transplantation. This review tries to summarize existing results of therapeutic revascularization using stem cell and to outline mechanism of their action.
Keywords:
lower extremity limb ischemia – stem cells – critical limb ischemia – diabetes mellitus
Sources
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Labels
Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain management Dental HygienistArticle was published in
Journal of Czech Physicians
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