The clefts as inborn defects
Authors:
Miloslav Kuklík
Authors‘ workplace:
Genetické oddělení, Praha
3
Published in:
Čas. Lék. čes. 2013; 152: 185-191
Category:
Review Article
Overview
The article refers usual facial clefts, which are not rare anomalies. Relation to other forms of so-called midline defects (limb clefts) is indicated. Syndromic and unusual clefts are rarer than isolated non-syndromic clefts. Clinical features, including minimal symptomatology, etiopathogenesis and population frequency are discussed. From the diagnostic point of view specific, prenatal, postnatal and differential diagnostic approaches are recognized. Preventive aspects, therapy and management of the disease (for cleft lip and palate defects, median cleft palate, broad spectrum of neural tube defects including anencephaly, limb clefts etc.) are important. We estimated the empiric risk of the recurrence and suggest methods for preconceptional preventive care.
Keywords:
cheilognathopalatoschizis – cleft palate – neural tube defects – limb clefts – etiopatogenesis – heredity – empiric risks and preconceptional care
Sources
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Labels
Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain management Dental HygienistArticle was published in
Journal of Czech Physicians
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