The role of pathology in the predictive oncology of solid tumours
Authors:
Pavel Fabian
Authors‘ workplace:
Masarykův onkologický ústav Brno, Oddělení onkologické a experimentální patologie
Published in:
Čas. Lék. čes. 2010; 149: 462-463
Category:
Review Article
Overview
Recently, a new generation of pharmacons that are aimed to hit specific molecular targets has entered the oncology. Currently, testing of tumour tissue for the presence of particular molecules is needed. These molecular entities predict probability of response to the targeted therapy. On a model of steroid hormone receptors and HER2 status testing a process of the predictive diagnostics is demonstrated. A contemporary concept of predictive oncology in the Czech Republic consisting of six „Predictive Oncology Laboratories“ is described. Surgical pathology is shown as a key partner in the predictive oncology system.
Key words:
predictive oncology.
Sources
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