Prediction and Monitoring of Severe Acute Pancreatitis
Authors:
R. Gürlich 1,2; P. Maruna 2; J. Špičák 3
Authors‘ workplace:
Klinika transplantační chirurgie IKEM, Praha
1; Ústav patologické fyziologie 1. LF UK, Praha
2; Klinika hepatogastroenterologie IKEM, Praha
3
Published in:
Čas. Lék. čes. 2006; 145: 437-441
Category:
Review Article
Overview
Twenty to thirty percent patients with acute pancreatitis develop severe acute pancreatitis with high mortality and morbidity rate. Markers of severity of acute pancreatitis are clinically important for the early diagnosis of complications. We reviewed the literature for markers of acute pancreatitis. on their relevance for prediction of severe pancreatitis are given. Several markers can predict severe cases of acute pancreatitis with a different positive and negative predictive value. Useful predictors of severity may include serum procalcitonin and urinary trypsinogen activation peptide at the admission, serum interleukins-6 and -8 at 24 h, and serum C-reactive protein (CRP) in 48 hours interval. The valuable marker for daily monitoring appears to be serum procalcitonin.
Key words:
severe acute pancreatitis, monitoring, diagnostic.
Labels
Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain management Dental HygienistArticle was published in
Journal of Czech Physicians
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