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Role of Intestine in Immunity Mechanisms


Authors: T. Fučíková
Authors‘ workplace: Ústav imunologie a mikrobiologie 1 . LF UK a VFN, Praha
Published in: Čas. Lék. čes. 2005; 144: 614-616
Category: Review Article

Overview

The intestinal mucosa represents important primary interface with the external environment. The mucosal immunity posses the ability to differentiate between non-pathogenic microbial agents (non-inflammatory immune reaction) and pathogens (inflammatory immune response). The defence mechanisms of intestinal mucosa due to extensive nonadaptive and adaptive immune reactions facilitate both inductive and effector side of immune response. The oral tolerance is dependent on the mucous intestinal immunity and modulates the systemic immune reactivity. 

Key words:
enterocytes, Paneth cells, mucous immunity, defensins, M cells.


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Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain management Dental Hygienist
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