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Polypharmacotherapy in Clinical Gerontology


Authors: P. Weber;  M. Kriška 1;  H. Meluzínová;  K. Dítětová;  M. Wawruch 1
Authors‘ workplace: Klinika interní, geriatrie, ošetřovatelství a praktického lékařství LF MU a FN, Brno 1Farmakologický ústav LF UK, Bratislava
Published in: Čas. Lék. čes. 2004; : 547-551
Category:

Overview

Multimorbidity frequently develops in old age and it is usually accompanied with pharmacotherapy of elderlypatients. The growing number of seniors and comparatively low attention given to this reality among the medicalcommunity makes the problem highly significant for the practical medicine. Solution requires in the broad medicalcommunity a deeper knowledge of gerontopharmacotherapy and of its specific features, including the pharmacodynamicsand pharmacokinetics in elderly organism. Non-geriatric physicians will face in their daily clinical praxisthe questions of drug interactions and undesirable general and local side effects. Moreover, some foods, beveragesor preservatives can influence the pharmacological effect. Due to multimorbidity in the senescence, such problemscan be linked to large geriatric syndromes (instability with downfalls, immobility, decubitus, incontinency, intellectualand sensory defects of vision and hearing).

Key words:
Geriatrics, multimorbidity, polypharmacotherapy, drug interactions, pharmacokinetics, pharmacodynamics,compliance.

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Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain management Dental Hygienist
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