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proLékaře.cz / Journals / Internal Medicine / 2023 - E-5

Steroid responsive encephalopathy associated with autoimmune thyroiditis as a cause of acuteencephalopathy

Czech version

Authors: Milan Maretta 1;  Alexandra Lacková 1;  Hedviga Wagnerová 2;  Eva Feketeová 1;  Zuzana Gdovinová 1
Authors‘ workplace: Neurologická klinika UPJŠ LF a UN LP v Košiciach 1;  I. interná klinika UPJŠ LF a UN LP v Košiciach 2
Published in: Vnitř Lék 2023; 69(E-5): 25-29
Category: Case Reports
doi: https://doi.org/10.36290/vnl.2023.068

Overview

Steroid-responsive encephalopathy associated with autoimmune thyroiditis (SREAT), known as Hashimoto’s encephalopathy (HE), represents a heterogeneous group of neurological and neuropsychiatric symptoms associated with a presence of antithyroid antibodies in case of other causes of encephalopathy were excluded. Clinical symptoms most commonly includes acute onset of encephalopathy, behaviour changes and cognitive dysfunction, epileptic seizures as well as cerebellar and extrapyramidal symptoms. Corticoids provides rapid and sustained therapeutic benefit in most patients and only a few patients require other immunosuppressive therapy such as plasmapheresis, intravenous immunoglobulins, or others. We present the cases of two patients with acute onset of encephalopathy, status epilepticus based on SREAT, with rapid improvement after steroid treatment.

Keywords:

Steroid therapy – SREAT – status epilepticus

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Diabetology Endocrinology Internal medicine
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Internal Medicine

Issue E-5
2023 Issue E-5
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