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Complement deficiencies


Authors: Marta Sobotková
Authors‘ workplace: Ústav imunologie 2. LF UK a FN v Motole
Published in: Vnitř Lék 2020; 66(6): 346-352
Category: Main Topic

Overview

Complement system plays a crucial role in innate imunity. Complement deficiencies are often associated with severe infections, usually meningoccocal, pneumococcal or caused by Haemophilus influenzae, or with autoimmune diseases, especially systemic lupus erythematodes. Inherited complement deficiencies are very rare although their prevalence in population may be underestimated due to lower availability of adequate laboratory testing. Acquired complement deficiencies accompany other underlying diseases and often are caused by increased consumption and only partial. 

Keywords:

infection – Complement – complement deficiency – autoimmune disease


Sources

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Labels
Diabetology Endocrinology Internal medicine

Article was published in

Internal Medicine

Issue 6

2020 Issue 6

Most read in this issue
Topics Journals
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