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Use of idarucizumab in clinical practice: a case report


Authors: Libuše Husová
Authors‘ workplace: Centrum kardiovaskulární a transplantační chirurgie, Brno
Published in: Vnitř Lék 2019; 65(5): 377-378
Category: Case reports

Overview

Budd-Chiari syndrome is a serious condition which in chronic course leads to the development of liver cirrhosis. Anti­coagulant treatment of this syndrome is fully indicated and in the treatment can be used dabigatran. Advanced cirrhosis of the liver due to this disease can be an indication for a liver transplant. In this case, it is a great advantage the existence of an antidote to dabigatran (idarucizumab) in order to adjust the coagulation ratios and prevent bleeding disorders. Referred to a case report describes the first experience with idarucizumab in context with liver transplant in a patient with Budd-Chiari syndrome

Keywords:

antidote – bleeding – dabigatran – direct oral anticoagulants (DOAC) – idarucizumab – liver transplant


Sources
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Diabetology Endocrinology Internal medicine
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