Incretins have changed and continue to change treatment strategy for type 2 diabetes

Czech version

Authors: M. Kvapil
Authors‘ workplace: Interní klinika 2. lékařské fakulty UK a FN Motol Praha, přednosta prof. MUDr. Milan Kvapil, CSc., MBA
Published in: Vnitř Lék 2011; 57(11): 916-918
Category: Birthday

Overview

Incretins are a novel class of drugs indicated for therapeutic intervention in patients with type 2 diabetes. They provide effective and safe therapy. Their advantages include low risk of hypoglycaemia and positive effect on body weight. Literature published so far consistently evidences reduced cardiovascular risk. If long-term prospective studies confirm such an effect, incretin therapy will, together with metformin, become the first line treatment for type 2 diabetes.

Key words:
type 2 diabetes mellitus – gliptins – GLP-1 receptor agonists – cardiovascular risk

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