Olfaction and gustation in diabetes

Czech version

Authors: Š. Svačina
Authors‘ workplace: III. interní klinika 1. lékařské fakulty UK a VFN, Praha, přednosta prof. MUDr. Štěpán Svačina, DrSc., MBA
Published in: Vnitř Lék 2007; 53(5): 483-485
Category:

Overview

U diabetu jsou přítomny poruchy čichu a chuti. V případě chuti spíše porucha souvisí se specifickými komplikacemi diabetu, u čichu spíše s diabetickou makroangiopatií. Patologické pocení při jídle (gustatory sweating) je dnes nejdůležitějším fenoménem z oblasti čichu a chuti v diabetologii. Poruchy čichu a chuti hrají podle experimentů asi určitou úlohu v oblasti patogeneze diabetu a jeho komplikací. Ovlivnění čichu a chuti je i oblastí potenciální významnou pro léčbu diabetu.

Klíčová slova:
čichové funkce - chuťové funkce - patologické pocení při jídle - specifické diabetické komplikace - obezita

Sources

1. Bhatia S, Sharma KN. Taste impairment for glucose in diabetic PTC tasters and non-tasters. Diabetes Res Clin Pract 1991; 12: 193-199.

2. Blair DI, Sagel J, Taylor I. Diabetic gustatory sweating. South Med J 2002; 95: 360.

3. Bramerson A, Johansson L, Ek L et al. Prevalence of olfactory dysfunction: the skovde population-based study. Laryngoscope 2004; 114: 733-737.

4. Hajnal A, Covasa M, Bello NT. Altered taste sensitivity in obese, prediabetic OLETF rats lacking CCK-1 receptors. Am J Physiol Regul Integr Comp Physiol 2005; 289: R1675.

5. Harv Mens Health Watch 2005; 9: 8. On call.

6. Karlsson AC, Lindroos AK, Lissner L et al. Evidence for gender-specific associations between leptin and olfaction. J Gend Specif Med 2002; 5: 25-32.

7. Kawaguchi H, Murata K. Electric gustatory threshold in diabetics and its clinical significance. Nippon Jibiinkoka Gakkai Kaiho 1995; 98: 1291-1296.

8. Kettaneh A, Fain O, Stirnemann J et al. Taste disorders. Rev Med Interne 2002; 23: 622-631.

9. Kleinschmidt EG. Olfactometric results of the olfactory function in diabetics. Z Gesamte Inn Med 1978; 33: 901-904.

10. Kulaga HM, Leitch CC, Eichers ER et al. Loss of BBS proteins causes anosmia in humans and defects in olfactory cilia structure and function in the mouse. Nat Genet 2004; 36: 994-998.

11. Moltrecht M, Michel O. The woman behind Frey's syndrome: the tragic life of Lucja Frey. Laryngoscope 2004; 114: 2205-2209.

12. Ninomiya Y, Sako N, Imai Y. Enhanced gustatory neural responses to sugars in the diabetic db/db mouse. Am J Physiol 1995; 269: R930-R937.

13. Nolte D, Gollmitzer I, Loeffelbein DJ et al. Botulinum toxin for treatment of gustatory sweating. A prospective randomized study. Mund Kiefer Gesichtschir 2004; 8: 369-375.

14. Peretianu D, Deleanu A, Tanase F. Gustative sensitivity to glucose improvement in diabetics after sulphonylurea. Rev Roum Physiol 1990; 27: 115-120.

15. Perros P, MacFarlane TW, Counsell C et al. Altered taste sensation in newly-diagnosed NIDDM. Diabetes Care 1996; 19: 768-770.

16. Reich SG, Grill SE. Gustatory sweating: Frey syndrome. Neurology 2005; 65: E24.

17. Richardson BE, Vander Woude EA, Sudan R et al. Altered olfactory acuity in the morbidly obese. Obes Surg 2004; 14: 967-969.

18. Shaw JE, Parker R, Hollis S et al. Gustatory sweating in diabetes mellitus. Diabet Med 1996; 13: 1033-1037.

19. Suzuki Y, Suzuki S, Hinokio Y et al. Diabetes associated with a novel 3264 mitochondrial tRNA(Leu)(UUR) mutation. Diabetes Care 1997; 20: 1138-1140.

20. Svačina Š Metabolické účinky psychofarmak. Praha: Triton 2004.

21. Tsunoda K, Osada K, Komai M et al. Effects of dietary biotin on enhanced sucrose intake and enhanced gustatory nerve responses to sucrose seen in diabetic OLETF rat. J Nutr Sci Vitaminol (Tokyo) 1998; 44: 207-216.

22. Urman JD, Bobrove AM. Diabetic gustatory sweating successfully treated with topical glycopyrrolate: report of a case and review of the literature. Arch Intern Med 1999; 159: 877-878.

23. Vannucci SJ, Koehler-Stec EM, Li K et al. GLUT4 glucose transporter expression in rodent brain: effect of diabetes. Brain Res 1998; 797: 1-11.

24. Weinstock RS, Wright HN, Smith DU. Olfactory dysfunction in diabetes mellitus. Physiol Behav 1993; 53: 17-21.