#PAGE_PARAMS# #ADS_HEAD_SCRIPTS# #MICRODATA#

Serum creatinine concentration and renal function (new insight into an old problem)


Authors: O. Schück;  V. Teplan;  I. Smrčková;  J. Skibová;  M. Štollová
Authors‘ workplace: Klinika nefrologie IKEM, Praha, přednosta prof. MUDr. Vladimír Teplan, DrSc., a Subkatedra nefrologie IPVZ, Praha, vedoucí prof. MUDr. Vladimír Teplan, DrSc.
Published in: Vnitř Lék 2005; 51(6): 725-727
Category: Reviews

Overview

In the brief review current possibilities of assessment of glomerular filtration rate based on single non-adjusted serum creatinine concentrations (SKr) are analysed and when so-called adjusted values of SKr are necessary to be used. In terms of adjusted value of SKr Cockcroft-Gault equation and prediction of GF based on abbreviated MDRD (Modification of Diet in Renal Disease) equation are analysed in more detail.

Key words:
serum creatinine concentration – glomerular filtration prediction – abbreviated MDRD equation


Sources

1. Cockcroft D, Gault MK. Prediction of creatinine clearance from serum creatinine. Nephron 1976; 16 : 31–41.

2. KIDOQI Clinical Practice Guidelines for Chronic Kidney Disease: evaluation, classification and stratification. Am J Kidney Dis 2002; 39(Suppl 1): S1–S266.

3. Levey AS, Bosch YP, Lewis JB et al. A more accurate method to estimate glomerular filtration rate from serum creatinine: A New Prediction Equation. Ann Intern Med 1999; 130: 461–470.

4. Mitch WE, Collier VU, Walser M. Creatinine metabolism in chronic renal failure. Clin Sci 1980; 58: 327–335.

5. Perrone RD, Madias NE, Levey AS. Serum creatinine as an index of renal function: new insights into old concepts. Clin Chem 1992; 38: 1993–1953.

6. Rehberg PB. Studies on kidney function I. The rate of filtration and reabsorption in the human kidney. Biochem J 1926; 20: 447–460.

7. Schück O, Teplan V, Jabor A et al. Glomerular filtration rate estimation in patients with advanced chronic renal insufficiency based on serum cystatin C levels. Nephron Clin Pract 2003; 93: c146–c151.

8. Schück O, Smrčková I, Teplan V et al. Nová metoda stanovení glomerulární koncentrace kreatininu, močoviny a albuminu (MDRD). Vnitř Lék 2004; 50: 507–509.

9. Shemesh O, Golbletz H, Kriss IP et al. Limitations of creatinine as a filtration marker in glomerulopathic patients. Kidney Int 1985; 28: 830–38.

10. Schwartz GJ, Haycock GB, Edelman CM et al. A simple estimate of glomerular filtration rate in children derived from body length and plasma creatinine. Pediatrics 1976; 58: 259–263.

Labels
Diabetology Endocrinology Internal medicine

Article was published in

Internal Medicine

Issue 6

2005 Issue 6

Most read in this issue
Topics Journals
Login
Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.

Login

Don‘t have an account?  Create new account

#ADS_BOTTOM_SCRIPTS#