Specific clinical features of late-onset rheumatoid arthritis
Authors:
MUDr. Jan Klán 1; MUDr. Hana Ciferská; Ph.D. 2; Prof. MUDr. Eva Topinková, CSc. 1
Authors‘ workplace:
Geriatrická klinika 1. LF UK a VFN, Praha
1; Revmatologický ústav, Praha
2
Published in:
Geriatrie a Gerontologie 2014, 3, č. 1: 18-24
Category:
Review Article
Overview
Diseases of the musculoskeletal system are one of the most common causes of disability in elderly patients. In this article we discuss clinical features of late onset rheumatoid arthritis (LORA), which is defined as having developed past the age of 65 years. LORA can be often misdiagnosed due to differential diagnosis problems characteristic for the elderly. LORA often has different clinical manifestation in comparison to classic cases of rheumatoid arthritis. The new diagnostic approaches and new drugs were introduced during the last decade. The main goal of treatment is to achieve remission and to prevent irreversible joint damage by timely and effective therapy. The disease modifying anti-rheumatic drugs (DMARD) are the baseline therapy of rheumatoid arthritis, however new biological drugs that appeared throughout the last decade are increasingly being used, especially in patients with severe forms of rheumatoid arthritis, with history of DMARD failure.
Key words:
rheumatoid arthritis – old age – LORA – disability – DMARD – biological therapy
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Geriatrics General practitioner for adults Orthopaedic prostheticsArticle was published in
Geriatrics and Gerontology
2014 Issue 1
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