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Urinary tract infections - risk factors for resistant pathogen infection


Authors: R. Tahotný;  S. Krčméry
Authors‘ workplace: UNsP Milosrdní bratia, II. Klinika geriatrie LF UK, Bratislava
Published in: Geriatrie a Gerontologie 2012, 1, č. 2: 71-76
Category: Original Article/Study

Overview

Antimicrobial treatment of urinary tract infections mostly begins in clinical practice empirically from many reasons. A result of antimicrobial treatment especially depends on an antimicrobial susceptibility of causing uropathogens. Prediction of the antimicrobial susceptibility of causing uropathogens is the necessary condition of the selection of an adequate empiric treatment. Information about local distribution of uropathogens and susceptibility serve for this purpose. Furthermore risk factors for uroinfection caused by uropathogens resistant to antimicrobials should be taken into consideration. The aim of our study was an assessment of possible connection among prevalence of uropathogens resistant to antimicrobials and selected patient`s risk factors (sex, urinary catheter presence, clinical presentation of the uroinfection). Methods: From 2006–2007, all uropathogens cultured from the urine of hospitalized patients at our department were retrospectively analyzed. The uropathogens were assigned to groups according sex, urinary catheter presence and clinical presentation of the uroinfection. A relation among the susceptibility to given antibiotics and patient` s risk factors were analyzed.

Results and conclusions:
Antimicrobial resistance to all five analyzed antibiotics was significantly higher in uropathogens cultivated from urine samples of patients with upper urinary tract infection and patients with urinary catheter. Antimicrobial resistance to only three from analyzed antibiotics was significantly higher in uropathogens cultivated from urine samples of men.

Key words:
antimicrobial resistance – uropathogens – urinary tract infection – risk factors


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