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Survival after resection of oesophageal cancer


Authors: J. Šafránek 1;  J. Geiger 1;  J. Šebek 1;  P. Hošek 2
Authors‘ workplace: Univerzita Karlova v Praze Lékařská fakulta v Plzni ;  Chirurgická klinika Přednosta: prof. MUDr. Vladislav Třeška, DrSc. 1;  Biomedicínské centrum Vědecký ředitel: doc. MUDr. Milan Štengl, Ph. D. 2
Published in: Prakt. Lék. 2018; 98(2): 69-72
Category: Of different specialties

Overview

Methods:
A retrospective analysis of a set of patient after resection of the oesophagus for carcinoma in a period of 5 years, from the point of view of the survival time for the type and stage of the carcinoma, was performed. The patients underwent open procedures, thoracolaparotomies, or two-hole procedures with anastomoses in the chest, or, possibly, cervical circular stapler anastomoses.

Results:
Total of 71 patients was operated on for carcinoma, 50 of them underwent surgeries for adenocarcinoma, and 20 patients were operated for squamous-cell carcinoma and 1 for a non-differentiated form of carcinoma. 30-day mortality recorded was 7.9%. The average hospital stay was 21 days (10–99 days). Relaparotomy was performed in 4 cases, rethoracotomy was needed in 6 cases and tracheostomy was necessary in 9 cases, all of them for the reason of postoperative complications. Anastomosis insufficiency was recorded in 5 cases (6.6%). 3-year survival in the 5-year file was 28.4% (11.5–45.3%), which was 29.6% for adenocarcinoma and 23.2% for squamous-cell carcinoma. No significant difference in survival was found in the group of adenocarcinoma patients (50) versus squamous-cell carcinoma patients (20) p = 0.413, node affection N0 (24) vs. higher N (40): p = 0.288, and the carcinoma stages I (12), II (16) and III and higher (41), p = 0.671.

Conclusion:
The prognosis of oesophageal carcinoma despite radical surgery remains unfavorable, in our set it was not statistically significantly influenced by TMN classification, nor the type of carcinoma.

Keywords:
oesophageal carcinoma – overall survival – complications


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