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Adrenal carcinoma – pitfalls of diagnosis


Authors: Z. Šafránková 1;  V. Třeška 2;  V. Liška 2;  J. Šafránek 2
Authors‘ workplace: AMBULANCE 010 s. r. o. ambulance praktického lékaře, Břasy 1;  Chirurgická klinika, FN Plzeň přednosta: prof. MUDr. V. Třeška, DrSc. 2
Published in: Prakt. Lék. 2010; 90(10): 614-617
Category: Case Report

Overview

Adrenal cancer is a rare type of malignity. The main risk comes from late diagnosis and the subsequent restrictions for possible treatments. A typical symptom is slow expression of Cushing’s syndrome. We present a case report of a 43-year-old female. Her problems started as face and neck swelling and mild progress soft hypercorticalism. Clinical diagnosis was late and complicated. Initially it was considered of chest or mediastinal pathology, then primary liver tumour was considered. At the time of correct diagnosis the patient’s clinical picture did not allow for radical or palliative surgical treatment. Oncology treatment (selective tumour chemoembolization) did not reduce the rapid progression of the malignant process and the patient died.

Key words:
adrenal cancer, Cushing’s syndrome, liver chemoembolization.


Sources

1. Třeška V. Primární maligní nádory jater, s. 202-203. In: Speciální chirurgie. Praha: Nakladatelství Karolinum 2006.

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4. Norton, J.A., Li, M., Gillary, J. et al. Cushing’s syndrome Original Research Article. Current Problems in Surgery 2001, 38, 7, p. 448-545.

5. Venkatesan, A.M., Locklin, J., Dupuy, D.E. et al. Percutaneous Ablation of Adrenal Tumors. Review Article. Techniques in Vascular and Interventional Radiology 2010, 13, 2, p. 89-99.

6. Rescorla, F.J. Malignant adrenal tumors. Seminars in Pediatric Surgery, 2006, 15, 1, p. 48-56.

7. Hsieh, M.H., Lin, Z.Y., Chuang, W.L. et al. Management of Bilateral Adrenal Metastases from Hepatocellular Carcinoma: A Case Report. The Kaohsiung Journal of Medical Sciences 2005, 21, 8, p. 371-376.

8. Kršek. M., Widimský, J. Jr. Choroby kůry nadledviny, s. 937-939. In: Vnitřní lékařství. Třetí, přepracované a doplněné vydání: Praha. Galén a Nakladatelství Karolinum 2006, s. 937-939.

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