#PAGE_PARAMS# #ADS_HEAD_SCRIPTS# #MICRODATA#

Tuberculosis – still a health problem


Authors: P. Čermák 1;  M. Havelková 2
Authors‘ workplace: Fakultní Thomayerova nemocnice s poliklinikou, Praha Oddělení klinické mikrobiologie Primář: doc. MUDr. Pavel Čermák, CSc. 1. lékařská fakulta Univerzity Karlovy v Praze Ústav klinické biochemie a laboratorní diagnostiky Přednosta: prof. MUDr. Tomáš Zima, 1;  Státní zdravotní ústav, Praha Národní referenční laboratoř pro mykobakterie Ředitel: MUDr. Milan Bořek 2
Published in: Prakt. Lék. 2009; 89(12): 692-697
Category: Diagnostis

Overview

Tuberculosis is still a major health problem, especially in developing countries. Nearly 2 million people die from tuberculosis each year. Extremely drug-resistant and multidrug-resistant tuberculosis strains present serious problems for the efficient control of this disease. Conventional methods for the identification of M. tuberculosis and detection of drug-resistance are slow and cumbersome. Determination of the genome sequence of M. tuberculosis has facilitated the development of new molecular assays. These new methods can be performed rapidly and offer high sensitivities and specificities. They can also be used for the detection of drug resistance. This review describes the current possibilities for the laboratory diagnosis of tuberculosis.

Key words:
tuberculosis, laboratory diagnosis, interferon gamma.


Sources

1. Altare, F., Durandy, A., Lammas, D. et al. Impairment of mycobacterial immunity in human interleukin-12 receptor deficiency. Science 1998, 280, p. 1432-1435.

2. Brosch, R., Gordon, S.V., Marmiesse, M. et al. A new evolutionary scenario for the Mycobacterium tuberculosis complex. Proc. Natl. Acad. Sci. U.S.A. 2002, 99, p. 3684–3689.

3. Cooper, A.M., Flynn, J.L. The protective immune response to Mycobacterium tuberculosis. Cur. Opin. Immunol. 1995, 7, p. 512-516.

4. Diel, R., Ernst, M., Doscher, G. et al. Avoiding the effect of BCG vaccination in detecting Mycobacterium tuberculosis infection with a blood test. Eur. Respir. J. 2006, 28, p. 16-23.

5. Dinnes, J., Deeks, J., Kunst, H. et al. A systematic review of rapid diagnostic tests for the detection of tuberculosis infection. Health. Technol. Asses. 2007, 11, p. 1-196.

6. Ernst, J.D., Trefeno-Nunez, G., Banaiee, N. Genomics and the evolution, pathogenesis, and diagnosis of tuberculosis. J. Clin. Invest. 2007, 117, p. 1738–1745.

7. Espinal, M.A., Simonsen, L., Laszlo, A. et al. Anti-tuberculosis drug resistance in the world, report no. 2: Prevalence and trends [on line]. 1st ed. Geneva: WHO, c. 2000 [cit. 2009-10-21]. Dostupný z WWW: <http://www.whqlibdoc.who.int/hq/2000/WHO_CDS_TB_2000.278_intro.pdf>

8. Ewann, F., Jackson, M., Pethe, K. et al. Transient requirement of the PrrA-PrrBTwo component system for early intracellular multiplication of Mycobacterium tuberculosis. Infect. Immun. 2002, 70, p. 2256-2263.

9. Franco-Alvarez de Luna, Ruiz, F., Gutierrez, J., Casal, M. Evaluation of the GenoType mycobacteria direct assay for detection of Mycobacterium tuberculosis complex and four atypical mycobacterial species in clinical samples. J. Clin. Microbiol. 2006, 44, p. 3025-3027.

10. Gagneux, S., DeRiemer, K., Van, T. Variable host-pathogen compatibility in Mycobacterium tuberculosis. Proc. Natl. Acad. Sci. U.S.A. 2006, 103, p. 2869–2873.

11. Gamboa, F., Fernandez, G., Padilla, E. et al. Comparative evaluation of initial and new versions of the Gen-Probe amplified Mycobacterium tuberculosis direct test for direct detection of Mycobacterium tuberculosis. J. Clin. Microbiol. 1998, 36, p. 684-689.

12. Gao, L.Y., Guo, S., McLaughlin, B. et al. A mycobacterial virulence gene cluster extending RD1 is required for cytolysis, bacterial spreading and ESAT-6 secretion. Mol. Microbiol. 2004, 53, s. 1677–1693.

13. Havelková, M., Šimáková, T., Príkazský, V. Výroční zpráva o mykobykteriologické diagnostice v České republice v roce 2007. [on line]. 2008-12-3 [cit. 2009-10-21]. Dostupný na WWW: <http://www.szu.cz/tema/prevence/vyrocni-zprava-o-mykobykteriologicke-diagnostice-v-ceske.html>

14. Hillemann, D., Rusch-Gerdes, S., Richter, E. Evaluation of the GenoType MTBDRplus assay for rifampin and isoniazid susceptibility testing of Mycobacterium tuberculosis strains and clinical specimens. J. Clin. Microbiol. 2007, 45, p. 2635–2640.

15. Huebner, R.E., Schein, M.F., Bass, J.B. Jr. The tuberculin skin test. Clin. Infect. Dis. 1993, 17, p. 968–975.

16. International Consortium on Tuberculosis. Why study tuberculosis? [on line]. 2008 [cit. 2009-10-21]. Dostupný na WWW: <http:// www2.ku.edu/~lba/Test/TB/ICTM.html>

17. Kamerbeek, J., Schouls, L., Kolk, A., et al. Simultaneous detection and strain differentiation of Mycobacterium tuberculosis for diagnosis and epidemiology. J. Clin. Microbiol. 1997, 35, p. 907–914.

18. Kim, J.H., Lee, S.Y., Sin, C. et al. NRAMP1 genetics polymorphisms as a risk factor oftuberculous pleurisy. Int. J. Tuberc. Lung. Dis. 2003, 7, p. 370-375.

19. Lemaitre, N., Sougakoff, W., Truffot-Pernot, C. et al. Use of DNA fingerprinting for primary surveillance of nosocomial tuberculosis in a large urban hospital: detection of outbreaks in homeless people and migrant workers. Int. J. Tuberc. Lung. Dis. 1998, 2, p. 390–396.

20. Macela, A. a kol. Infekční choroby a intracelulární parazitismus bakterií. 1. vyd. Praha: Grada, 2006. 216 s. ISBN 80-247-0664-4.

21. Marais, B.J., Brittle, W., Painczyk, K. et al. Use of light-emitting diode fluorescence microscopy to detect acid-fast bacilli in sputum. Clin. Infect. Dis. 2008, 47, p. 203-207.

22. Mole, R.J., Maskell, T.W.O. Phage as a diagnostic - the use of phage in TB diagnosis. J. Chem. Technol. Biotechnol. 2001, 76, p. 683–688.

23. Moorem D., Mendoza, D., Gilman, R.H. et al. Tuberculosis Working Group in Peru. Microscopic observation drug susceptibility assay, a rapid, reliable diagnostic test for multidrug-resistant tuberculosis suitable for use in resource-poor settings. J. Clin. Microbiol. 2004, 42, p. 4432–4437.

24. Muzaffar, R., Batool, S., Aziz, F. et al. Evaluation of the FASTPlaqueTB assay for direct detection of Mycobacterium tuberculosis in sputum specimens. Int. J. Tuberc. Lung. Dis. 2002, 6, p. 635–640.

24. Neonakis, I.K., Gitti, Z., Krambovitis, E., Spandidos, E.A. Molecular diagnostic tools in mycobacteriology. J. Microbiol. Methods 2008, 75, p. 1-11.

25. Oelemann, M.C., Diel, R., Vatin, V. et al. Assessment of an optimized mycobacterial interspersed repetitiveunit-variable-number tandem-repeat typing system combined with spoligotyping for population-based molecular epidemiology studies of tuberculosis. J. Clin. Microbiol. 2007, 45, p. 691–697.

26. Pai, M., Kalantri, S., Heda, K. New tools and emerging technologies for the diagnosis of tuberculosis: Part I. Latent tuberculosis. Expert. Rev. Mol. Diagn. 2006, 6, p. 413-422.

27. Pai, M., Zwerling, A., Menzies, D. Systematic review: T-cell-based assays for the diagnosis of latent tuberculosis infection: an update. Ann. Intern. Med. 2008, 149, p. 177-184.

28. Palomino, J., Martin, A., Von Groll, A., Portaels, F. Rapid culture-based methods for drug-resistance detection in Mycobacterium tuberculosis. J. Microbiol. Methods 2008, 75, p. 161-166.

29. Piersimoni, C., Scaparo, C., Piccoli, P. et al. Performance assessment of two commercial amplification assays for direct detection of Mycobacterium tuberculosis complex from respiratory and extrapulmonary specimens. J. Clin. Microbiol. 2002, 40, p. 4138-4142.

30. Piersimoni, C. Scaparo, C. Relevance of commercial amplification methods for direct detection of Mycobacterium tuberculosis complex in clinical samples. J. Clin. Microbiol. 2003, 41, p. 5355-5365.

31. Richardson, E.T., Samson, D., Banaei, N. Rapid Identification of Mycobacterium tuberculosis and nontuberculous mycobacteria by multiplex, real-time PCR. J. Clin. Microbiol. 2009, 47, p. 1497-1502.

32. Richeldi, L. An update on the diagnosis of tuberculosis infection. Am. J. Respir. Crit. Care. Med. 2006, 174, p. 736-742.

33. Richter, E., Rusch-Gerdes, S., Hillemann, D. Evaluation of the GenoType Mycobacterium assay for identification of mycobacterial species from cultures. J. Clin. Microbiol. 2006, 44, p. 1769–1775.

34. Russo, C., Tortoli, E., Menichella, D. Evaluation of the new GenoType Mycobacterium assay for identification of mycobacterial species. J. Clin. Microbiol. 2006, 44, p. 334–339.

35. Shah, N.S., Wright, A., Bai, G.H. et al. Worldwide emergence of extensively drug-resistant tuberculosis. Emerg. Infect. Dis. 2008, 13, p. 380-387.

36. Sharma, M., Sethi, S., Mishra, B. et al. Rapid detection of mutations in rpoB gene of rifampicin resistant Mycobacterium tuberculosis strains by line probe assay. Indian J. Med. Res. 2003, 117, p. 76–80.

37. Shenai, S., Rodrigues, C., Mehta, A. Rapid speciation of 15 clinically relevant mycobacteria with simultaneous detection of resistance to rifampin, isoniazid, and streptomycin in Mycobacterium tuberculosis complex. Int. J. Infect. Dis. 2009, 13, p. 46-58.

38. Soini, H., Musser, J.M. Molecular diagnostic of mycobacteria. Clin. Chem. 2001, 47, p. 809-814.

39. Tortoli, E., Marcelli, F. Use of the INNO LiPA Rif.TB for detection of Mycobacterium tuberculosis DNA directly in clinical specimens and for simultaneous determination of rifampin susceptibility. Eur. J. Clin. Microbiol. Infect. Dis. 2007, 26, p. 51–55.

40. Tortoli, E., Mariottini, A., Mazzarelli, G. Evaluation of INNO-LiPA MYCOBACTERIA v2: improved reverse hybridization multiple DNA probe assay for mycobacterial identification. J. Clin. Microbiol. 2003, 41, p. 4418–4420.

41. vanHelden, P.D. The economic divide and tuberculosis. Tuberculosis is not just a medical problem, but also a problem of social inequality and poverty. ENBO Rep. 2003, 4, Spec., S24-S28.

42. Wilson, S.M., al-Suwaidi, Z., McNerney, R. et al. Evaluation of a new rapid bacteriophage-based method for the drug susceptibility testing of Mycobacterium tuberculosis. Nat. Med. 1997, 3, p. 465–468.

43. Wrigtt, A., Zignol, M. Anti-tuberculosis drug resistance in the world: fourth global report [on line]. 1st ed. Genova: WHO, c. 2008 [cit. 2009-10-21]. Dostupný z WWW: <http://www.whqlibdoc. who.int/hq/2008/WHO_CDS_TB_2008.394_eng. pdf>

44. Zhang, P., Summer, W.R., Bagby, G.J., Nelson, S. Innate immunity and pulmonary host defense. Immunol. Rev. 2000, 173, p. 39-51.

45. Zignol, M., Hosseini, M.S., Wright, A. et al. Global influence of multi-drug resistant tuberculosis. J. Infect. Dis. 2006, 194, p. 479-485.

Labels
General practitioner for children and adolescents General practitioner for adults
Topics Journals
Login
Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.

Login

Don‘t have an account?  Create new account

#ADS_BOTTOM_SCRIPTS#